Clinico- Immunological Parallels in Chronic Obstructive Bronchitis in AdolescentsMuhayyo Kholjigitova*
Department of Hospital Therapy and endocrinology, Samarkand Medical Institute, Uzbekistan
- *Corresponding Author:
- Muhayyo Kholjigitova
Department of Hospital Therapy and endocrinology
Samarkand Medical Institute, Samarkand, Uzbekistan
E-mail: [email protected]
Received date: July 04, 2014; Accepted date: September 23, 2014; Published date: September 27, 2014
Citation: Kholjigitova M (2014) Clinico- Immunological Parallels in Chronic Obstructive Bronchitis in Adolescents. J Pulm Respir Med 4:206. doi:10.4172/2161-105X.1000206
Copyright: © 2014 Kholjigitova M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The aim of this work was to study the concentration of IL-8 in conjunction with clinical and functional parameters of the COB in adolescents. Surveyed 52 teenagers and young men suffering from COB aged 11 to 21 years old. The control group consisted of 22 healthy individuals. Options for clinical COB 3 subgroups were identified. To examine the extent of production of IL-8, depending on the severity of the disease showed that IL- 8 levels in the serum increased significantly PC. It is noted that higher concentrations of IL- 8 cytokine was observed in patients with severe chronic obstructive bronchitis. ERF also made observations in these patients, depending on the stage and severity of disease. When functional examination in adolescents with COB were indicators showed a reduction in FVC, FEV1, PEF, MEF25, MEF50, MEF75, MEF25-75 which corresponded to a mixed disorders of pulmonary ventilation function with a predominance of obstructive variant. Thus, in patients with COB stradayushih adolescent relationship marked functional performance parameters of pulmonary cytokine status, in particular IL- 8.