alexa Clomiphene Stimulation Test in Men Abusing Anabolic-Androgenic Steroids for Long Time | OMICS International | Abstract
ISSN: 2157-7536

Journal of Steroids & Hormonal Science
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Clomiphene Stimulation Test in Men Abusing Anabolic-Androgenic Steroids for Long Time

Medras M1,2, Jozkow P2*, Terpilowski L3 and Zagocka E4

1Department of Endocrinology, Diabetology and Isotope Treatment, Wroclaw Medical University, ul. Pasteura 4, 50-367 Wroclaw, Poland

2Department of Sports Medicine, University School of Physical Education, ul, Paderewskiego 35, 51-612 Wroclaw, Poland

3Department of Emergency Medical Services, Wroclaw Medical University, ul. Pasteura 4, 50-367 Wroclaw, Poland

4Laboratory of Male Infertility, ul. Kosciuszki 108A/18, 50-441 Wroclaw, Poland

*Corresponding Author:
Pawel Jozkow
Department of Sports Medicine
University School of Physical Education
ul. Paderewskiego 35, 51-612 Wroclaw, Poland
Tel: +48 71 347 33 06
Fax: +48 71 347 30 53
E-mail: [email protected]

Received date: February 27, 2014; Accepted date: April 23, 2014; Published date: April 30, 2014

Citation: Medras M, Jozkow P, Terpilowski L, Zagocka E (2014) Clomiphene Stimulation Test in Men Abusing Anabolic-Androgenic Steroids for Long Time. J Steroids Hormon Sci 5:129. doi:10.4172/2157-7536.1000129

Copyright: © 2014 Medras M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Objective: Androgenic-anabolic steroids (AAS) are commonly used by athletes and recreational athletes. In some cases they induce persistent anabolic steroid-induced hypogonadism (ASIH).

Design: In an observational study we assessed the function of the pituitary-gonadal axis in a series of men with suspected ASIH.

Methods: Clomiphene stimulation test (CST) was performed in 13 hypogonadal adult men with previous, prolonged exposure to AAS. We evaluated the response of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and total testosterone (T) to 50 mg of clomiphene daily administered for a week.

Results: Mean concentrations of hormones before and after clomiphene administration were respectively (mean ± SD): 3 ± 1.2 and 8.3 ± 2 mIU/ml for LH; 3 ± 1.1 and 10 ± 14.6 mIU/ml for FSH; and 2.3 ± 0.6 and 7.2 ± 1.7 ng/ml for T (p<0.001).

Conclusions: Men with ASIH, after a long-time withdrawal of AAS, present an intact reaction of gonadotropins and testosterone to clomiphene stimulation.


Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7