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Coding by Different Diameter Impedance, Detection Method of Microspheres Which are Used to Produce Liquid Biochip | OMICS International | Abstract
ISSN: 2155-6210

Journal of Biosensors & Bioelectronics
Open Access

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Research Article

Coding by Different Diameter Impedance, Detection Method of Microspheres Which are Used to Produce Liquid Biochip

Zhanke Wang1,2*, Tian Hu3, Xiaolu Hu2, Tao Song4, Wangshen Lei2, Honghua Zhou5, Xiao Yan5, Hong Dai5 and Jin Chang4*

1Department of Biomedical Engineering, School of Precision Instrument and Optoelectronics, Tianjin University, Tianjin, China

2The 94th Hospital of PLA, Nanchang, Jiang Xi, China

3The First Clinical Medicine School of Nanchang University, Nanchang, Jiang Xi, China

4Institute of Nanobiotechnology; School of material science and engineering; Tianjin University; Tianjin, China

5Tekangtechnology Limited company of Jiangxi, Nanchang, Jiang Xi, China

*Corresponding Author:
Jin Chang
Institute of Nanobiotechnology
School of material science and engineering
Tianjin University, Tianjin, China
Tel: 079127401821
Fax: 079127401821
E-mail: [email protected]

Zhanke Wang
Department of Biomedical Engineering
School of Precision Instrument and Optoelectronics
Tianjin University, Tianjin, China
Tel: 07918848127
Fax: 07918848106
E-mail: [email protected]

Received Date: August 13, 2011; Accepted Date: December 08, 2011; Published Date: January 07, 2012

Citation: Wang Z, Hu T, Hu X, Song T, Lei W, et al. (2012) Coding by Different Diameter Impedance, Detection Method of Microspheres Which are Used to Produce Liquid Biochip. J Biosens Bioelectron 3:111. doi: 10.4172/2155-6210.1000111

Copyright: © 2012 Wang Z, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

This research was aiming at developing liquid biochip which was coded by impedance microsphere of different diameter and providing research foundation for its detecting device. Adopting the method of loading constant current source between both ends of micropore in ruby, it were tested that three sorts of microspheres’ impedance with particle sizes of 2μm, 5μm, 10μm. It was resultantly found that microsphere diameter is in direct proportion to impedance and voltage between both ends of micropore. In other words, microsphere of different size could be distinguished from each other by their impedance. Our research drew the indication that impedance of microspheres in different sizes could be theoretically calculated as well as measured and automatically distinguished, offering experimental and theoretical foundation for liquid biochip development.

Keywords

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World Congress on Biosensors and Bioelectronics

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