Coexistence of Inflammatory Bowel Disease and GravesÃ¢ÂÂ DiseaseToru Shizuma*
Department of Physiology, School of Medicine, Tokai University, Japan
- *Corresponding Author:
- Toru Shizuma
Department of Physiology
School of Medicine, Tokai University, Japan
E-mail: [email protected]
Received Date: January 5, 2016;Accepted Date: January 25, 2016; Published Date: February1, 2015
Citation: Shizuma T (2016) Coexistence of Inflammatory Bowel Disease and Graves’ Disease. J Immuno Biol 1:1000102. doi: 10.4172/jib.1000102
Copyright: © 2015 Shizuma T. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The coexistence of Graves’ disease (GD) and inflammatory bowel disease (IBD), particularly Crohn’s disease (CD) and ulcerative colitis (UC), has not been well documented. Therefore, this report reviews the literature regarding coexisting IBD and GD. Reported cases of concomitant IBD and GD are rare; 16 cases of concomitant UC and GD and 3 cases of concomitant CD and GD were found. Among the 19 reported cases of concomitant IBD and GD, IBD developed before GD in 8 (42.1%) cases, GD developed before IBD in 9 (47.4%) cases, and both conditions coexisted in 2 (10.5%) cases. Therefore, there was no evidence for a tendency of a preceding disease between IBD and GD. The interval between diagnoses of IBD and GD varied from 0 year to 20 years. Furthermore, there was no evidence indicating that patients with concomitant IBD and GD had poorer prognoses than those with IBD but without GD.