Co-Existence of Relapsing Remitting Multiple Sclerosis and HLA B27 Positive Ankylosing Spondylitis in a Malay Male: A Rare OccurrenceViswanathan S* and Kamil MKM
Hospital Kuala Lumpur, Department of Neurology, Jalan Pahang, Kuala Lumpur, MY 50586, Malaysia
- *Corresponding Author:
- Viswanathan S
Hospital Kuala Lumpur, Department of Neurology
Jalan Pahang, Kuala Lumpur, MY 50586, Malaysia
Email: [email protected]
Received date: February 27, 2017; Accepted date: March 23, 2017; Published date: March 30, 2017
Citation: Viswanathan S, Kamil MKM (2017) Co-Existence of Relapsing Remitting Multiple Sclerosis and HLA B27 Positive Ankylosing Spondylitis in a Malay Male: A Rare Occurrence. J Mult Scler 4:198. doi:10.4172/2376-0389.1000198
Copyright: © 2017 Viswanathan S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Ankylosing spondylitis (AS) and multiple sclerosis (MS) are two different chronic inflammatory autoimmune conditions with unclear etiopathogenesis. One is a rheumatological disorder while the other is a neurological one. Current literature on an association between these two conditions is limited. Furthermore, early recognition of potential cases with both conditions co-existing is important as there have been very rare reports on the occurrence of demyelinating diseases or unmasking of latent MS in patients with ankylosing spondylitis treated with anti-TNFα. This has important therapeutic implications for patients at such risk.