alexa Cognitive Impairments in Children with Systemic Lupus a
ISSN: 2161-0487

Journal of Psychology & Psychotherapy
Open Access

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Research Article

Cognitive Impairments in Children with Systemic Lupus and Neuropsychiatric Lupus

Estrella Godinez-Villanueva1, Guillermina Yañez2 and Elizabeth Hernández-Echeagaray1*

1Unidad de Biomedicina, FES-I, Universidad Nacional Autónoma de México, México

2Unidad de Investigación Interdisciplinaria en Ciencias de la Salud y la Educación, México

*Corresponding Author:
Elizabeth Hernández-Echeagaray
Laboratorio de Neurofisiología del Desarrollo y la Neurodegeneración Unidad de Biomedicina
FES-I, Universidad Nacional Autónoma de México Av. de Los Barrios # 1
Los Reyes Iztacala C. P. 54090 Tlalnepantla, México
+ 52 55 5623 1333 Ext 39787
+ 52 55 5623-1138
[email protected]

Received date: April 10, 2017; Accepted date: May 03, 2017; Published date: May 10, 2017

Citation: Godínez-Villanueva E, Yañez G, Hernández-Echeagaray E (2017) Cognitive Impairments in Children with Systemic Lupus and Neuropsychiatric Lupus. J Psychol Psychother 7:300. doi:10.4172/2161-0487.1000300

Copyright: © 2017 Godínez-Villanueva E, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Objective: The aim of the present study was to determine neurocognitive profile in Children with Systemic (SLE) and Neuropsychiatric Lupus (NPSLE) describing differences in the seven cognitive areas proposed by the ACR (attention, memory, visuospatial processing, language, problem solving, processing speed, and executive function) between children with SLE and those with NPSLE and to understand the level of cognitive deterioration in children afflicted by SLE with and without neuropsychiatric changes. Method: Children with SLE and with NPSLE were evaluated using the Wechsler Intelligence Scale for Children (WISC-IV) and some selected subtests of the Neuropsychological Assessment for Children (NAC), which allowed us to measure the 7 cognitive areas proposed by the ACR. Both, SLE and NPSLE children performances were compared to scores obtained by children without any affection. Results: The area’s most affected in the NPSLE group were attention, working memory, processing speed, memory, and visuospatial ability; in the SLE group, the area’s most affected were processing speed, visuospatial ability, planning, and auditory memory. Conclusion: Based on our findings, it is concluded that frequently in both groups cognitive decline is present since early stages of illness, being more important in the NPSLE group. These deficiencies are heterogenous and with a multi-domain pattern.


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