Comment onÃ¢Â€Âœ Classification of Advanced Stages of ParkinsonÃ¢Â€Â™s Disease: Translation into Stratified TreatmentsÃ¢Â€ÂPierre Kolber1,2 and Rejko Krüger1,2*
- *Corresponding Author:
- Rejko Krüger
Luxembourg Centre for Systems Biomedicine (LCSB)
University of Luxembourg, Esch-Sur-Alzette
E-mail: [email protected]
Received date: April 23, 2017; Accepted date: April 26, 2017; Published date: April 30, 2017
Citation: Kolber P, Krüger R (2017) Comment on “Classification of Advanced Stages of Parkinson’s Disease: Translation into Stratified Treatments”. Int J Neurorehabilitation 4:261. doi:10.4172/2376-0281.1000261
Copyright: © 2017 Kolber P, et al.. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Parkinson’s disease (PD) is increasingly recognized as a heterogeneous disorder combining equally diverse motor and non-motor symptoms, with a complex interplay and different individual presentations, especially in the advanced stages of the disease. Current classifications and related stage-adapted therapeutic recommendations still lack of precision, as traditional concepts of advanced PD (advPD) are mainly based on milestones of motor disabilities. In this short review, we present the concepts delineated by Krüger and colleagues published in the ‘Journal of Neural Transmission’ on current classifications for advPD and novel directions for future clinical trials, a precision medicine approach by empowerment of patients and their involvement in therapeutic decisions.