Commentary on Ã¢ÂÂGroup-Based Exercise Combined with Dual-Task Training Improves Gait but not Vascular Health in Active Older Adults without DementiaÃ¢ÂÂ - Missed Opportunities for Mediation AnalysesGregory MA1,2,3*
- *Corresponding Author:
- Michael A Gregory, PhD
Institut de Cardiologie de Montréal Research Centre
Rm. 2450, 5000 Rue. Belanger, Montreal
E-mail: [email protected]
Received date: April 25, 2017; Accepted date: April 28, 2017; Published date: April 30, 2017
Citation: Gregory MA (2017) Commentary on “Group-Based Exercise Combined with Dual-Task Training Improves Gait but not Vascular Health in Active Older Adults without Dementia” - Missed Opportunities for Mediation Analyses. Int J Neurorehabilitation 4:265. doi:10.4172/2376-0281.1000265
Copyright: © 2017 Gregory MA. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This commentary considers the implications of the findings related to the effect of a community-based, multiple modality and dual-task exercise training program in the Archives of Gerontology and Geriatrics. Findings from this study suggest that participants who performed the multiple modality and dual-task exercise intervention experienced greater improvements in global cognition, greater elevations in dual-task gait speed and dual-task step-length and greater reductions in dual-task stride time variability when compared to participants who did not perform the dual-task component of the exercise training program. The ability of exercise to impart cognitive and other physiological benefits has been long understood; however, the mechanisms that facilitate these training-induced improvements remain elusive. Mediation analyses provide a unique avenue to investigate the relationship between various physiological measures and can provide insight related to the causal sequence that drives the beneficial physiological and psychological response to an intervention. Recent works have incorporated mediation analyses within their study designs and the insight provided therein has revealed a number of intriguing intricacies with respect to cognition in aging and the effect of exercise on the body and brain. Mediation analyses are rarely utilized in neurophysiological research; however, the complex phenomenological relationships that can be revealed using this method will be crucially required for the identification of factors responsible for improvements in cognition following pharmacological or lifestyle-based interventions, and the development of effective management strategies for older adults with cognitive impairment.