Commentary on the Phototoxicity and Absorption of Vitamin B2 and Its Degradation Product, Lumichrome
Katsuhito Kino*, Akira Nakatsuma, Hiromi Nochi, Yoshimitsu Kiriyama, Takuro Kurita, Takanobu Kobayashi and Hiroshi Miyazawa
Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, Japan
- *Corresponding Author:
- Katsuhito Kino
Kagawa School of Pharmaceutical Sciences
Tokushima Bunri University, 1314-1, Shido
Sanuki, Kagawa 769- 2193, Japan
E-mail: [email protected] kph.bunri-u.ac.jp
Received Date: July 28, 2015 Accepted Date: August 12, 2015 Published Date: August 15, 2015
Citation: Kino K, Nakatsuma A, Nochi H, Kiriyama Y, Kurita T, et al. (2015) Commentary on the Phototoxicity and Absorption of Vitamin B2 and Its Degradation Product, Lumichrome. Pharm Anal Acta 6:403. doi: 10.4172/2153-2435.1000403
Copyright: © 2015 Kino K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
In this commentary, we present two views related to the study of riboflavin (vitamin B2): (i) future research into the photo toxicity of riboflavin and its photo-degradation product, lumichrome, should consider effects under visible light and ultraviolet (UV) light in skin because the photochemistry of these reactions differ; and (ii) future research should consider the possibility that excess lumichrome, which is metabolized from riboflavin by intestinal bacteria and is much less water-soluble than riboflavin, could be more readily absorbed and lead to symptoms that resemble those of fat-soluble vitamins.