alexa Comparative Evaluation of Hypolipidemic Effects of Ethanolic Extract of Fruit of <em>Piper chaba</em> and <em>Piper nigrum</em> on Albino Rabbits | OMICS International | Abstract
ISSN: 2090-2697

Journal of Forensic Biomechanics
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Comparative Evaluation of Hypolipidemic Effects of Ethanolic Extract of Fruit of Piper chaba and Piper nigrum on Albino Rabbits

Sana Sarfaraz1*, Rahila Najam2, Iqbal Azhar3Ghulam Sarwar4

1Department of Pharmacology, Faculty of Pharmacy, Jinnah University for Women Karachi-74600 Pakistan

2Department of Pharmacology, Faculty of Pharmacy, University of Karachi, Karachi-74600 Pakistan

3Department of Pharmacognosy, Faculty of Pharmacy, University of Karachi, Karachi-74600 Pakistan

4Department of Pharmacognosy, Faculty of Pharmacy, Jinnah University for Women Karachi-74600 Pakistan

*Corresponding Author:
Sana Sarfaraz
Department of Pharmacology, Faculty of Pharmacy
Jinnah University for Women, Karachi-74600, Pakistan
Tel: +923222087342
E-mail: [email protected]

Received date: March 24, 2016; Accepted date: April 12, 2016; Published date: April 19, 2016

Citation: Sarfaraz S, Najam R, Azhar I, Sarwar G (2016) Comparative Evaluation of Hypolipidemic Effects of Ethanolic Extract of Fruit of Piper chaba and Piper nigrum on Albino Rabbits. Forensic Biomechanics 7:128. doi:10.4172/2090-2697.128

Copyright: ©2016 Sarfaraz S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.



Abstract

Background: One of the main causes of cardiovascular disease is increased cholesterol in the body. Unfortunately the trend of cardiovascular diseases is still very prevalent and no longer specific to adult population.

Objective: The present study was designed to evaluate the effect of ethanolic extract of fruit of Piper chaba and Piper nigrum on lipid profile and to evaluate which extract is more beneficial and could be helpful in treatment of cardiovascular diseases.

Methodology: The study was conducted on albino rabbits weighing 1000 gms-1600 gms. The animals were administered ethanolic extract of Piper chaba 150 mg/kg and Piper nigrum 250 mg/kg which was further diluted in Di methyl sulfoxide (DMSO) and dose was adjusted in ml based on weight of animals. After 7 days dosing animal’s blood was drawn and assessed for Cholestrol, HDL and LDL.

Results and Discussion: Our study showed that Ethanolic extract of Piper chaba possess significant hypolipidemic effects and lowers chlolestrol and LDL levels while shows significant effect on HDL levels too. Whereas Piper nigrum extract elevated cholesterol and HDL levels significantly and lowered LDL levels.

Conclusion: Piper chaba extract can be used in hyperlipidemia. Piper nigrum extract can be used to increase HDL and lower LDL. Further studies can be carried out to check effect on other organs for preferring the extracts in particular conditions.

Keywords

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7