Comparative Study of Nanobioactive Glass Quaternary System 46S6
- *Corresponding Author:
- AA Mostafa
University of Rennes 1
UMR CNRS 6226, 263 av. du général leclerc
35042 Rennes cedex, France
National Research Centre (NRC), Cairo, Egypt
E-mail: [email protected]; [email protected]
Received Date: Decenber 31, 2013; Accepted Date: January 05, 2014; Published Date: January 12, 2014
Citation: Mabrouk M, Mostafa AA, Oudadesse H, Wers E, Lucas-Girot A, et al. (2014) Comparative Study of Nanobioactive Glass Quaternary System 46S6. Bioceram Dev Appl 4:072. doi:10.4172/2090-5025.1000072
Copyright: © 2014 Mabrouk M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided theoriginal author and source are credited.
Different bioactive glass systems have been prepared by sol-gel. However, the production of Na2O-containing bioactive glasses by sol–gel methods has proved to be difficult as the sodium nitrate used in the preparation could be lost from the glass structure during filtration and washing. The aim of this study was to prepare the quaternary system 46S6 of bioactive glass by modified sol-gel techniques with a decrease in the time of gelation. In addition, compare the behaviour of the prepared sol-gel bioactive glass system by its corresponding prepared by melting. The obtained glasses were characterized by using several physicochemical techniques; XRD, FTIR, TEM and SEM beside the effect of the glass particles on the viability of osteoblast like cells (Saos-2). Results show that nanopowders 40-60 nm of 46S6 glass system had been prepared by modified sol-gel (acid-base reaction) method at 600°C in just three days at 600°C. Cell viability by MTT assay confirmed the effectiveness of the prepared nanobioactive glass.