alexa Comparative Study of Two Therapies Pharmacological Based a Ivermectin and Febendazol by <em>Strongyles</em> Control Intestinal in Thorougbreds Horses | OMICS International | Abstract
ISSN: 2157-7579

Journal of Veterinary Science & Technology
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Research Article

Comparative Study of Two Therapies Pharmacological Based a Ivermectin and Febendazol by Strongyles Control Intestinal in Thorougbreds Horses

Sneiry Pérez-Álvarez1, Keysamir Rojas-Mujica1, Héctor Bello3, Diana Villoria3 and Abelardo Morales2,3*

1School of Pharmacy University of Santa María, Venezuela

2Department of Pathology Faculty of Veterinary Science Central University of Venezuela, Venezuela

3Racetrack Animal Health Division “La Rinconada” Caracas-Venezuela, Venezuela

*Corresponding Author:
Abelardo Morales
Department of Pathology
Faculty of Veterinary Science
Central University of Venezuela, Venezuela
E-mail: [email protected]

Received date: August 07, 2013; Accepted date: September 29, 2013; Published date: October 01, 2013

Citation: Pérez-Álvarez S, Rojas-Mujica K, Bello H, Villoria D, Morales A (2013) Comparative Study of Two Therapies Pharmacological Based a Ivermectin and Febendazol by Strongyles Control Intestinal in Thorougbreds Horses. J Veterinar Sci Technol 4:144. doi:10.4172/2157-7579.1000144

Copyright: © 2013 Pérez-Álvarez S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

The aim of this study was to comparative of two therapies pharmacological based ivermectin and febendazole by Strongyles control intestinal in Thoroughbreds horses. Were study 110 horses all of 2 years old (55 Stallion and 55 Mares), in the Racetrack “La Rinconada” Caracas-Venezuela. A stool test was performed prior to treatment to each horse. Group 1: 50 horses were evaluated before treatment, using a stool test, then was given Ivermectin (0.2 mg/kg) 1% 7 ml, with reassessment intramuscularly coprological at 7 days. Group 2: 50 horses were evaluated before treatment, using a stool test, Fenbendazole was later administered (5 mg/kg) 18.8% oral paste 12 g. With reassessment coprological at 7 days. Group 3: 10 equines those not administered drug therapy, alone parasite burden was assessed using a fecal examination by Willis test. Anthelmintics effectiveness was conducted by counting fecal drug-treated group and the untreated control group. The results Group1 with Ivermectin 2.38 EPG showed pre-treatment and post treatment 7 days EPG 0.48. The group2 with Fenbendazole obtained 2.66 EPG and 7 days post treatment was obtained 0.06 EPG. Group 3 without medication present the following day 1.9 EPG value and then at 7 days 2 EPG. Comparing the effectiveness of both drug treatment and fenbendazole ivermectin antiparasitic indicate that fenbendazole base is more effective against the equine intestinal Strongylus, taking a percentage of 97% in comparison with specifically macrocyclic lactones which Ivermectin obtained a much lower drug efficacy throwing only 76%.

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