Comparing the Effect of One Stage Full Mouth Disinfection Versus Quadrant-Wise Scaling and Root Planing on Clinical Parameters and Salivary Inflammatory Biomarkers in Chronic Periodontitis Patients
- *Corresponding Author:
- Shirmohammadi A
Department of Periodontics, Dental Faculty
Tabriz University of Medical Sciences
Tabriz 51666-14711, Iran
Tel: +98 411 335 59 65
Fax: +98 411 334 69 77
Cell: +98 914 411 2272
E-mail: [email protected]
Received date December 07, 2011; Accepted date January 24, 2012; Published date January 26, 2012
Citation: Eskandari A, Babaloo Z, Shirmohammadi A, Khashabi E (2012) Comparing the Effect of One Stage Full Mouth Disinfection Versus Quadrant- Wise Scaling and Root Planing on Clinical Parameters and Salivary Inflammatory Biomarkers in Chronic Periodontitis Patients. Dentistry 2:118. doi: 10.4172/2161-1122.1000118
Copyright: © 2012 Eskandari A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background: We aimed to compare the efficacy of one stage full mouth disinfection versus the quadrant-wise scaling and root planing in terms of clinical parameters and inflammatory biomarkers screening.
Methods: Forty patients, with generalized moderate to severe chronic periodontitis, participated in the study. The test group received one stage full mouth disinfection (FMD). Quadrant wise scaling and root planing (Q-SRP) was performed for the control group. At baseline, 2 months and 4 months, Clinical parameters and salivary IL-1β and MMP-8 were measured.
Results: Both procedures resulted in statistically significant improvement in all of the measured parameters between the baseline and the 2 and 4 months (p<0.05%). No meaningful improvement was seen between the 2 and 4 months (p<0.05%) in both of the FMD and Q-SRP groups. There was no significantly difference between the study groups except for the MGI (P<0.05).
Conclusion: No statistically significant differences were found between FMD and Q-SRP.