alexa Comparison of Lateral Internal Sphincterotomy with Topical Nitroglycerine Treatment in Patients with Chronic Anal Fissure: A Prospective Randomised Study | Abstract
ISSN: 2161-1076

Surgery: Current Research
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Comparison of Lateral Internal Sphincterotomy with Topical Nitroglycerine Treatment in Patients with Chronic Anal Fissure: A Prospective Randomised Study

Fahri Yetisir1*, A. Ebru Salman2, Banu Yurekli3, Mustafa Aksoy2, Murat B.Yildirim1, Samet Yalcin4 and Mehmet Kilic4

1Atatürk Research and Training Hospital, General Surgery Department, Turkey

2Ataturk Research and Training Hospital, Anaesthesiology and Reanimation Department, Turkey

3Bozyaka Research and Training Hospital, Endocrinology, Turkey

4Assoc.Prof, Yildirim Beyazit University, General Surgery Department, Turkey

*Corresponding Author:
Fahri Yetisir
Ataturk Research and Training Hospital
Department of General Surgery, Turkey
Tel: +90 536 297 48 88
E-mail: [email protected]

Received date: October 18, 2012; Accepted date: October 27, 2012; Published date: November 02, 2012

Citation: Yetisir F, Salman AE, Yurekli B, Aksoy M, Yildirim MB, et al. (2012) Comparison of Lateral Internal Sphincterotomy with Topical Nitro-glycerine Treatment in Patients with Chronic Anal Fissure: A Prospective Randomised Study. Surgery Curr Res 2:123. doi:10.4172/2161-1076.1000123

Copyright: © 2012 Yetisir F, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Aim: Lateral Internal Sphincteromy (LIS) is considered as gold standard in the treatment of chronic anal fissure. However, LIS has complications such as gas and stool incontinence. The aim of the present study was to compare the results of LIS and 0.4% topical nitroglicerin treatment in patients with chronic anal fissure.

Method: 150 patients with Chronic Anal Fissure were prospectively randomised into two Groups of 75 subjects in each. Group I underwent LIS and Group 2 was administered topical nitroglicerin. All patients were given high fibre diet and phsyllium diet before and after the treatment. After follow up period, two Groups were compared in terms of postoperative complications, recurrence rates, loss of work days and patient satisfaction.

Results: Two Groups were similar in terms of demographic data and anal fissures. Recurrence was seen in 4 patients in Group I and 8 patients in Group II. Gas incontinence under stress developed in 7 patients in Group I, in no patient Group II. Anal itching and soiling occurred in 8 patients in Group I, in no patient Group II. In Group II, headache occurred in 12 patients during treatment. Duration of time to return to work and normal activity was longer in Group I.

Conclusion: It is our suggestion that topical nitroglicerin is as effective as surgery in the treatment of chronic anal fissure with absence of incontinence.


Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2019-20
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri and Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

ankara escort

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

pendik escort

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2019 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7