alexa Comparison of the Effects of Colloid Preload and Ephedrine Bolus Admınistration on Left Ventricular Loading and Quality of Spinal Anesthesia
ISSN: 2155-6148

Journal of Anesthesia & Clinical Research
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Research Article

Comparison of the Effects of Colloid Preload and Ephedrine Bolus Admınistration on Left Ventricular Loading and Quality of Spinal Anesthesia

Onur Özlü1, Süreyya Aydin2, Ebru Salman A3*, Mustafa Aksoy4 and Mustafa Çagatay5

1Anesthesiology and Reanimation Depatment, Diskapi Yildirim Beyazit Research and Educational Hospital, Ankara, Turkey

2Resident in Trainning, Anesthesiology and Reanimation Depatment, Diskapi Yildirim Beyazit Research and Educational Hospital, Ankara, Turkey

3Anesthesiologist, Atatürk Research and Trainning Hospital, Ankara, Turkey

4Anesthesiologist, Anesthesiology and Reanimation Department, Diskapi Yildirim Beyazit Research and Educational Hospital, Ankara, Turkey

5Microbiology Department, Diskapi Yildirim Beyazit Research and Educational Hospital, Ankara, Turkey

*Corresponding Author:
Ebru Salman A
Anesthesiologist
Atatürk Research and Trainning Hospital, Ankara, Turkey
E-mail: [email protected]

Received date: September 17, 2012; Accepted date: October 09, 2012; Published date: October 27, 2012

Citation: Özlü O, Aydin S, Ebru Salman A, Aksoy M, Çagatay M (2012) Comparison of the Effects of Colloid Preload and Ephedrine Bolus Administration on Left Ventricular Loading and Quality of Spinal Anesthesia. J Anesth Clin Res 3:247. doi: 10.4172/2155-6148.1000247

Copyright: © 2012 Özlü O, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: We aimed to investigate the effects of colloid preload or ephedrine bolus on ventricular wall stress by measuring plasma N terminal-Brain natriuretic peptide (NT-ProBNP) concentrations in patients undergoing arthroscopic knee surgery under spinal anesthesia. Methods: 60 patients ASA I-II, aged 20-60 were randomly assigned into two groups. Spinal anesthesia was induced with 0.5% 3 ml levobupivacaine. In Group K (n=30) patients received 500 ml of HES (130/0.4) solution 20 minutes prior to spinal anesthesia. In Group E (n=30) ephedrine 15 mg i.v was injected 1 minute after spinal anesthesia. SBP, DBP, MBP, HR were recorded before and 3,5,7,10,15,20,25,30,45,60,120,240 min. after spinal anesthesia spinal anesthesia and in both groups and in group K also recorded before preload. The plasma concentrations of NT-ProBNP were measured before and 1 and 3 hours after the spinal block.

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