Bioceramics Development and Applications
Open Access

Research Article

Comparison of Two Composites Developed to be Used as Bone Replacement – PMMA/Bioglass 45S5® Microfiber and PMMA/Hydroxyapatite

Lourdes Cristina de Albuquerque Haach^1*, Benedito de Moraes Purquerio¹, Nelson Ferreira Silva Jr², Ana Maria Minarelli Gaspar³ and Carlos Alberto Fortulan¹

¹ Department of Mechanical Engineering, University of São Paulo, Av. Trabalhador São-Carlense 400, CEP 13566-590 São Carlos (SP), Brazil

² Laboratory of Bioengineering, University of São Paulo, Av. Trabalhador São-Carlense 400 CEP 13566-590 São Carlos (SP), Brazil

³ Laboratory of Morfology, Universidade Estadual Paulista Júlio de Mesquita, Rua Humaitá 1680 CEP 14801-903, Araraquara, São Paulo (SP), Brazil

*Corresponding Author:

Lourdes Cristina de Albuquerque Haach
Department of Mechanical Engineering
University of São Paulo
Av. Trabalhador São-Carlense 400
CEP 13566-590 São Carlos (SP), Brazil
Tel: +551634153119
E-mail: [email protected]

Received Date: December 12, 2013; Accepted Date: December 12, 2013; Published Date: January 11, 2014

Citation: de Albuquerque Haach LC, de Moraes Purquerio B, Silva Jr NF, Minarelli Gaspar AM, Fortulan CA (2014) Comparison of Two Composites Developed to be Used as Bone Replacement – PMMA/Bioglass 45S5® Microfiber and PMMA/ Hydroxyapatite. Bioceram Dev Appl 4:071. doi: 10.4172/2090-5025.1000071

Copyright: © 2014 de Albuquerque Haach LC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Two types of polymer matrix composites were designed to use as bone replacement: PMMA+HA and PMMA+45S5® Blown Fibers. The materials were tested in vivo for 60 days and compared to two control groups: empty bone defect and porous PMMA. The histology results suggest that both materials provide a suitable scaffold for bone growth with the presence of newly formed bone tissue, blood vessels, osteocytes and osteoblasts cells. For a better understanding of the mechanical properties of scaffolds to bear physiological loads when implanted, compressive tests were carried out. The results showed difference in the compressive behaviour of the two composites, PMMA+HA specimens achieved higher values approaching 9.0 MPa of ultimate strength while PMMA+45S5® had values close to 8.0MPa. Both materials are suitable to bone replacement of small size areas.

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