Comparison Treatment of Vitiligo by Co-culture of Melanocytes Derived from Hair Follicle with Adipose-Derived Stem Cells with and without NB-UVBAhmed A Saleh1, Osama H Abdel-salam1, Hala G Metwally2, Hany A Abdelsalam1, Ayman M Hassan3 and Walaa S Sosa1*
- Corresponding Author:
- Walaa S Sosa
Dermatology and Andrology
Department Benha University, Egypt
E-mail: [email protected]
Received date: November 16, 2016; Accepted date: January 23, 2017; Published date: January 31, 2017
Citation: Saleh AA, Salam OHA, Metwally GH, Abdelsalam HA, Hassan MA, et al. (2017) Comparison Treatment of Vitiligo by Co-culture of Melanocytes Derived from Hair Follicle with Adipose-Derived Stem Cells with and without NB-UVB. Pigmentary Disorders 4:256. doi:10.4172/2376-0427.1000256
Copyright: © 2017 Saleh AA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Objective: The aim of this work is to evaluate treatment of vitiligo by co-culture of melanocytes derived from hair follicle with adipose-derived stem cells with (NB-UVB) and without (NB-UVB). Patients and methods: In this study, we used co culture of adipose derived stem cell with melanocytes derived from hair follicle in treating different types of stable resistant vitiligo, by two methods transplantation: group (A) exposed to (NB-UVB), group (B) did not expose to (NB-UVB). They are followed up for 3 months. Results: At the end of the follow up period which was 3 months group (A) showed better pigmentary response than group (B) and it was highly statistically significant. Stability, size, site and onset of vitiligo appeared to be important factors affecting treatment results. Using (NB-UVB) also after injection of the treatment showed more improvement in the treatment results. Conclusion: Co-culture of adipose derived stem cell with melanocytes derived from hair follicle could be a safe and effective method of treatment for stable localized vitiligo in patients resistant to other methods of therapy.