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Computational Annotation for Hypothetical Proteins of <em>Mycobacterium Tuberculosis</em> | OMICS International | Abstract
ISSN: 0974-7230

Journal of Computer Science & Systems Biology
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Research Article

Computational Annotation for Hypothetical Proteins of Mycobacterium Tuberculosis

S.Anandakumar and P. Shanmughavel1*

1Computational Biology and Bioinformatics Laboratory, Department of Bioinformatics,   Bharathiar University, Coimbatore – 641046, TamilNadu, India

*Corresponding Author:
Dr. P. Shanmughavel
Email : [email protected]

Received Date: August 28, 2008; Accepted Date: November 10, 2008; Published Date: December 26, 2008

Citation: Anandakumar S, Shanmughavel P (2008) Computational Annotation for Hypothetical Proteins of MycobacteriumTuberculosis. J Comput Sci Syst Biol 1:050-062. doi: 10.4172/jcsb.1000004

Copyright: © 2008 Anandakumar S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


There is rising death of humans worldwide by reason of tuberculosis. The current sequencing of the Mycobacteriumtuberculosis genome holds assure for the development of new vaccines and the design of new drugs. In this view, the functions prediction of genomic sequences for hypothetical proteins will invigorate our knowledge with reference to the identification of new drugs for tuberculosis. There are various function prediction methods available based on the on the assumption. The process accurate annotation for genes in newly sequenced genomes currently has been based on sequence similarity. In this work about 250 hypothetical proteins of Mycobacteriumtuberculosis taken functions were predicted using Bioinformatics web tools, BLAST, INTERPROSCAN, PFAM and COGs.


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