Congenital Chloride Losing Diarrhea
Ali Khairallah Alzahrani*
Head of Pediatric Department, Faculty of Medicine, Taif University, Saudi Arabia
- *Corresponding Author:
- Ali Khairallah AlZahrani
Consultant of Pediatrics and Head of Pediatric department
Faculty of Medicine, Taif University, Saudi Arabia
E-mail: [email protected]
Received Date: January 16, 2014; Accepted Date: February 21, 2014; Published Date: February 25, 2014
Citation: Alzahrani AK (2014) Congenital Chloride Losing Diarrhea. Pediat Therapeut 4:193. doi:10.4172/2161-0665.1000193
Copyright: © 2014 Alzahrani AK. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background: Congenital chloride-losing diarrhea is a medical emergency that become a mostly pediatric problem in many countries including Saudi Arabia. It is requiring early diagnostics and treatment to prevent severe dehydration and infant mortality.
Aim of the review: To summarize data on congenital chloride diarrhea including: incidence, pathophysiology and management.
Methods: Data are based on MEDLINE search for chloride losing diarrhea in addition to clinical experience in treatment of these cases.
Results: Life-long salt substitution with NaCl and KCl stabilizes fluid, electrolyte and acid-base balance. When early diagnosed and properly treated, the long-term outcome is favorable. Conclusions: This review summarizes data on congenital chloride diarrhea and provides guide lines of treatment.