alexa Congenital Linear Becker’s Nevus, with Underlying Breast Hypoplasia that Spontaneously Corrected during Pregnancy: Role of Androgen Receptors
ISSN: 2167-0870

Journal of Clinical Trials
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Case Report

Congenital Linear Becker’s Nevus, with Underlying Breast Hypoplasia that Spontaneously Corrected during Pregnancy: Role of Androgen Receptors

SJ Felton1*, Al-Niaimi F1, Thornton J2 and Lyon CC3
1Dermatology Centre, Salford Royal NHS Foundation Trust, UK
2Department of Pathology, Bradford Teaching Hospitals NHS Foundation Trust, UK
3Department of Dermatology, York Teaching Hospital NHS Foundation Trust, UK
Corresponding Author : Dr. S Felton
Dermatology Centre
Salford Royal NHS Foundation Trust
Stott Lane, Manchester, M6 8HD, UK
Tel: 44(0)161 2061011
Fax: 44(0)161 2061018
E-mail: [email protected]
Received December 19, 2012; Accepted December 29, 2012; Published December 31, 2012
Citation: Felton SJ, Al-Niaimi F, Thornton J, Lyon CC (2012) Congenital Linear Becker’s Nevus, with Underlying Breast Hypoplasia that Spontaneously Corrected during Pregnancy: Role of Androgen Receptors. J Clin Trials 2:125. doi:10.4172/2167-0870.1000125
Copyright: © 2012 Felton SJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

Becker’s nevus is a pigmented cutaneous hamartoma that is normally localized to the upper torso. It is more commonly found in adolescent males and may form part of the Becker’s nevus syndrome, in association with other features which may include overlying hypertrichosis, chest wall, breast or limb hypoplasia and scoliosis. Congenital and linear lesions have been reported but are very rare. We describe here a case of a congenital, linear nevus with histological features diagnostic of a Becker’s nevus, with associated underlying breast hypoplasia. We confirm increased androgen receptors within her nevus and consequently, when our patient became pregnant, her relative antiandrogen profile enabled physiological enlargement of the previously hypoplastic breast beneath this nevus

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