alexa Conotoxins and their Regulatory Considerations
ISSN: 2167-7689

Pharmaceutical Regulatory Affairs: Open Access
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Review Article

Conotoxins and their Regulatory Considerations

Parashar Thapa, Michael J Espiritu, Chino C Cabalteja and Jon-Paul Bingham*

Department of Molecular Biosciences and Bioengineering, College of Tropical Agriculture and Human Resources, University of Hawai’i, Honolulu, HI, 96822, USA

*Corresponding Author:
Jon-Paul Bingham
Department of Molecular Biosciences and Bioengineering
College of Tropical Agriculture and Human Resources
University of Hawaii, HI, 96822, USA
Fax: 808-965-3542
E-mail: [email protected]

Received date: April 16, 2014; Accepted date: May 05, 2014; Published date: June 02, 2014

Citation: Thapa P, Espiritu MJ, Cabalteja CC, Bingham JP (2014) Conotoxins and their Regulatory Considerations. Pharmaceut Reg Affairs 3:122. doi:10.4172/2167-7689.1000122

Copyright: © 2014 Thapa P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Venom derived peptides from marine cone snails, conotoxins, have demonstrated unique pharmacological targeting properties that have been pivotal in advancing medical research. The awareness of their true toxic origins and potent pharmacological nature is emphasized by their ‘select agent’ classification by the US Centers for Disease Control and Prevention. We briefly introduce the biochemical and pharmacological aspects of conotoxins, highlighting current advancements into their biological engineering, and provide details to the present regulations that govern their use in research.

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