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ISSN: 2161-1149

Rheumatology: Current Research
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Research Article

Content Validation of the Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue Scale in Moderately to Highly Active Rheumatoid Arthritis

Karen Kaiser1*, Sara Shaunfield1, Marla L. Clayman2, Eric Ruderman3 and David Cella1

1Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, 625 North Michigan Avenue, Suite 2700, Chicago, IL, 60611, USA

2American Institutes for Research, Chicago, IL, USA

3Department of Medicine-Rheumatology, Northwestern University Feinberg School of Medicine, USA

*Corresponding Author:
Karen Kaiser
Department of Medical Social Sciences
Northwestern University Feinberg School of Medicine
625 North Michigan Avenue, Suite 2700
Chicago, IL, 60611, USA
Tel: 312-503-3521
E-mail: [email protected]

Received date: February 26, 2016; Accepted date: April 21, 2016; Published date: April 25, 2016

Citation: Kaiser k, Shaunfield S, Clayman ML, Ruderman E, Cella D (2016) Content Validation of the Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue Scale in Moderately to Highly Active Rheumatoid Arthritis. Rheumatology (Sunnyvale) 6:193. doi: 10.4172/2161-1149.1000193

Copyright: © 2016 Kaiser K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Objective: Fatigue is one of the most burdensome symptoms of Rheumatoid Arthritis (RA), thus validated measures are needed to assess it in practice and research. Although performance and responsiveness of the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-Fatigue) has been demonstrated in moderately to highly active RA and several other conditions, the face and content validity of the instrument in this context has not been evaluated.

Methods: Semi-structured interviews were conducted with patients with moderately to highly active RA. Participant comments were analysed using a constant comparative approach, and findings were mapped to the FACIT-Fatigue to assess content validity.

Results: A total of 17 patients participated in the study; saturation was obtained after 16 interviews. Participants had been living with an RA diagnosis from 2 months to 36 years. Participants were primarily female (82%), white (59%), and mean age was 54. FACIT-Fatigue was found to have good face validity and strong content validity for RA. No significant gaps in content were identified. However, three items were found to be less relevant to RA fatigue: “I feel weak all over”, “I feel listless (‘washed out’)”, and “I am too tired to eat”. +

Conclusion: The FACIT-Fatigue has good face and content validity for patients with moderately to highly active RA. The instrument could be further tailored to RA patients by removing a few items deemed less relevant than others in this context; however, even those less-relevant items retained their relevance for a good number of patients.

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