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ISSN: 2329-6798

Modern Chemistry & Applications
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Review Article

Correlation between Bisphenol A Exposure and Adverse Health Effects

Michelle Kelley1,2, Armand G Ngounou Wetie1 and Costel C Darie1*
1Biochemistry & Proteomics Group, Department of Chemistry & Biomolecular Science, Clarkson University, USA
2Department of Biology, Clarkson University, USA
Corresponding Author : Costel C Darie
Biochemistry & Proteomics Group
Department of Chemistry & Biomolecular Science
Clarkson University, 8 Clarkson Avenue Potsdam
NY, 13699-5810, USA
Tel: 315-268-7763
Fax: 315-268-6610
E-mail: [email protected]
Received December 11, 2014; Accepted January 20, 2015; Published January 23, 2015
Citation: Kelley M, Wetie AGN, Darie CC (2015) Correlation between Bisphenol A Exposure and Adverse Health Effects. Mod Chem appl 3:147. doi: 10.4172/2329-6798.1000147
Copyright: © 2015 Kelley M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Bisphenol A is found in polycarbonate plastics and epoxy resins that make up many items that people use every day such as water bottles, toys and food packaging. There is much disagreement about how much BPA exposure is necessary to cause adverse health effects. In a study completed by the EPA, they found that people have not been exposed to levels high enough to have an effect on their health. A study by the CDC found BPA in 95% of the 394 of the adult urine samples tested, but impact human health is not yet clear. Many studies have found correlations between measurable amounts of BPA in the body and health effects including recurrent miscarriages, chromosomal abnormalities and polycystic ovarian syndrome. Exposure is particularly concerning in children, especially prenatal. This is because they have not yet developed UDP-glucuronosyltransferase, the primary BPA metabolizing enzyme. Also, studies of other species have found that unconjugated BPA can diffuse across the placenta, from a mother’s circulation to the fetus. Several studies have focused on the detection and removal of BPA from the environment. There is still a lot of research to be done to determine safe levels of BPA exposure for adults, children and animals to avoid detrimental health risks.

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