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ISSN: 2155-9880

Journal of Clinical & Experimental Cardiology
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  • Research Article   
  • J Clin Exp Cardiolog 2017, Vol 9(1): 566
  • DOI: 10.4172/2155-9880.1000566

Correlation between Mesenteric Fat Thickness and Characteristics of Coronary Artery Disease in Patients with Metabolic Syndrome

Wael Wagdy1,2*, Mostafa Ateya Mohamad1, Wael Refat Abd El Hamed1, Ahmed Kmal Motaweih1 and Mohamad Salem El Baz1
1Department of Cardiology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt
2Cardiology Department, Nasr City Police hospital, , Cairo, Egypt
*Corresponding Author : Wael Wagdy, Cardiology Department, Nasr City Police Hospital, Al Tayaran St., 7th District, Nasr City, Cairo, Postal Code, 11765, Egypt, Tel: 00201222802212, Email: [email protected]

Received Date: Jan 15, 2018 / Accepted Date: Jan 29, 2018 / Published Date: Feb 02, 2018


Background and aim: Metabolic syndrome (MetS) includes an assembly of conditions; the most important of which is obesity. The pandemic prevalence of obesity worldwide increased the awareness of MetS. Mesenteric fat thickness is linked to higher risk of coronary artery disease (CAD) complications which may lead to death. Although many studies were done on patients with MetS worldwide, studies on Egyptian patients are limited. Thus, here we examined the relationship between mesenteric fat thickness and the severity and prevalence of CAD among Egyptian patients with MetS.

Methods: Sixty-four patients with MetS were recruited in this prospective cohort study. We assessed the mesenteric fat, and carotid intima media thickness using ultrasonography. Moreover, we evaluated the coronary arteries using myocardial perfusion imaging, MSCT, and/or coronary angiography.

Results: Twenty-three patients had a mesenteric fat thickness less than 10 mm, while 41 patients had a mesenteric fat thickness equal to 10 mm or more. Severity and prevalence of CAD were significantly higher in patients with a mesenteric fat thickness of 10 mm or more (P<0.001, and 0.007). Moreover, there was a significant positive correlation between carotid intima media thickness and a number of diseased vessels in patients with CAD.

Conclusion: Our results suggest that mesenteric fat thickness and carotid intima media thickness are good indicators of the prevalence and severity of CAD in patients with MetS. More studies on a large number of the population are required to define MetS in Egyptian patients with MetS, especially in those with a higher risk of CAD.

Keywords: Metabolic syndrome (MetS); Mesenteric fat thickness (MFT); Waist circumference (WC); Coronary artery disease (CAD); Cardiovascular diseases (CVD); Obesity

Citation: Wagdy W, Mohamad MA, El Hamed WRA, Motaweih AK, El Baz MS (2018) Correlation between Mesenteric Fat Thickness and Characteristics of Coronary Artery Disease in Patients with Metabolic Syndrome. J Clin Exp Cardiolog 9: 569. Doi: 10.4172/2155-9880.1000566

Copyright: ©2018 Wagdy W, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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