alexa Correlation between QT-interval Duration and Treatment
ISSN: 2161-1459

Journal of Clinical & Experimental Pharmacology
Open Access

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Research Article

Correlation between QT-interval Duration and Treatment with Propranolol in Patients with Liver Cirrhosis

Lorena Mărieş* and Ioan Maniţiu

“Lucian Blaga” University of Sibiu, Bulevardul Victoriei 10, Sibiu 550024, Romania

*Corresponding Author:
Lorena Mărieş
15 Dîrstelor Street, Sibiu, Romania
Tel: +40745387973
E-mail: [email protected]

Received date: October 30, 2013; Accepted date: December 07, 2013; Published date: December 17, 2013

Citation: Maries L, Manitiu I (2013) Correlation between QT-interval Duration and Treatment with Propranolol in Patients with Liver Cirrhosis. Clin Exp Pharmacol 3:144. doi:10.4172/2161-1459.1000144

Copyright: © 2013 Maries L, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



We studied the effect of chronic treatment with propranolol on QT-interval duration in a group of patients with liver cirrhosis. It is known that they may have a secondary cardiac disease, the cirrhotic cardiomyopathy. As several studies have reported a reduction in QT-interval in these cases, we investigated this, knowing that there is frequently a prolonged QT-interval in cirrhotic cardiomyopathy.

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