Curative Intent Treatment for Colorectal Cancer with Isolated Brain Metastases: A Case Report
|Cynthia Cherfane1, Muneera R Kapadia2, Ron Schey1 and Adrian Holm1*|
|1Department of Internal Medicine, University of Iowa Roy J. and Lucille A. Carver College of Medicine, 200 Hawkins Drive, Iowa City, USA|
|2Department of Surgery, University of Iowa Roy J. and Lucille A. Carver College of Medicine, 200 Hawkins Drive, Iowa City, USA|
|Corresponding Author :||Adrian Holm
Department of Internal Medicine
University of Iowa Roy J. and Lucille
A. Carver College of Medicine, 200 Hawkins Drive
Iowa City, IA 52242, USA
E-mail: [email protected]
|Received January 10, 2014; Accepted February 18, 2014; Published February 25, 2013|
|Citation: Cherfane C, Kapadia RM, Schey R, Holm A (2014) Curative Intent Treatment for Colorectal Cancer with Isolated Brain Metastases: A Case Report. J Carcinog & Mutagen S10:002. doi: 10.4172/2157-2518.S10-002|
|Copyright: © 2014 Holm A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
Introduction: Brain metastases (BM) are a rare complication of colorectal cancer (CRC), typically presenting late in the course of the disease and are associated with other systemic metastases. Management of solitary brain metastases in colorectal cancer is still not well established.
Case presentation: We describe the case of a 65 year-old man presenting with a solitary brain metastasis as the first sign of colon cancer. The treatment approach included surgical resection of the brain lesion followed by resection of the primary tumor, systemic chemotherapy and local radiation therapy to the BM.
Conclusion: This curative intent approach has resulted in dramatically prolonged patient’s survival compared to the average reported in the literature, now nearly 2.5 years after presentation. Our case describes the feasibility of a multidisciplinary curative intent approach to solitary BM in CRC.