Current Indications, Techniques and Results of Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy for Intra-Abdominal Malignancies
Meagan Wademan, Jinny Ha, Harvinder Singh, Youdchitra Markan, Pormina Sharma, Karl Kasamon, Nimagada, Mitch Oh, Wendly Citron, Randy Cohen, Russel Deluca and Cherif Boutros*
Surgical Oncology, Medical Oncology and Radiation Oncology, Tate Cancer Center, Baltimore Washington Medical Center, University of Maryland Medical System, Glen Burnie, MD 21060, USA
- *Corresponding Author:
- Cherif Boutros
University of Maryland School of Medicine
Surgical Oncology, Tate Cancer Center
Baltimore Washington Medical Centre 305 Hospital Drive
Glen Burnie, MD 21061, USA
E-mail: [email protected]
Received date: September 28, 2012; Accepted date: November 19, 2012; Published date: November 23, 2012
Citation: Wademan M, Ha J, Singh H, Markan Y, Sharma P, et al. (2012) Current Indications, Techniques and Results of Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy for Intra-Abdominal Malignancies. Surgery Curr Res 2:125. doi:10.4172/2161-1076.1000125
Copyright: © 2012 Wademan M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Over the last decades, there has been a paradigm shift regarding the management of peritoneal dissemination of intra-abdominal malignancies. Previously believed to be an end-stage disease amenable only to palliative management, several studies have reported achieving significant survival advantage by applying cytoreduction of the tumour load with or without intraoperative hyperthermic intraperitoneal chemotherapy administration. It is hard to classify this procedure as curative despite the reported good results in achieving a reasonable 5-years survival. However, its ability to control the disease process is clearly recognized in different types of intra-abdominal malignancies and its role is better understood within the new concept of treating advanced cancer as a chronic disease. The aim of this review is to discuss the concept, techniques, results and complications of this approach. Current indications and future directions will also be emphasized.