alexa Current Progress in Enthesis Repair: Strategies for Interfacial Tissue Engineering | OMICS International | Abstract
ISSN: 2161-0533

Orthopedic & Muscular System: Current Research
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Special Issue Article

Current Progress in Enthesis Repair: Strategies for Interfacial Tissue Engineering

Jennifer Z. Paxton1*, Keith Baar2 and Liam M.Grover1

1TRAILab, School of Chemical Engineering, University of Birmingham, Edgbaston, B15 2TT, UK

2FMBLab, Department of Neurobiology, Physiology and Behavior, 1 Shields Ave, University of California, Davis, CA, 95616, USA

*Corresponding Author:
Jennifer Z. Paxton
TRAILab, School of Chemical Engineering
University of Birmingham
Edgbaston, B15 2TT, UK
E-mail: [email protected]

Received Date: November 17, 2011; Accepted Date: February 17, 2012; Published Date: February 17, 2012

Citation: Paxton JZ, Baar K, Grover LM (2012) Current Progress in Enthesis Repair: Strategies for Interfacial Tissue Engineering. Orthopedic Muscul Sys S1:003. doi:10.4172/2161-0533.S1-003

Copyright: © 2012 Paxton JZ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Complex interfaces have evolved at the junction between tissues of the musculoskeletal system to overcome
the problems of impedance mismatch. In this review, we have revisited the anatomy, development, injury and repair
of the interface between bone and tendon/ligament, also known as the osteotendinous/osteoligamentous junction
or enthesis. Specifically, the existing options for repair have also been discussed along with the current progress of
interfacial tissue engineers aiming to manufacture multiphase tissue constructs for repair of these complex interfaces
in vitro.

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