alexa Cutaneous Rosai-Dorfmann Disease in Autistic Patient: I
ISSN: 2165-7920

Journal of Clinical Case Reports
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Case Report

Cutaneous Rosai-Dorfmann Disease in Autistic Patient: Is there a Pathogenetic Correlation?

Caglia P*, Tracia A, Borzi L, Lucifora B, Tracia L, Spataro D and Amodeo C
Department of Surgical Sciences, Organ Transplantation and Advanced Technologies, Surgery Oncology, Unit University of Catania, Italy
Corresponding Author : Caglia Pietro
Department of Surgical Sciences
Organ Transplantation and Advanced Technologies
Surgery Oncology, Unit University of Catania, Italy
Received October 10, 2013; Accepted November 11, 2013; Published November 13, 2013
Citation: Caglia P, Tracia A, Borzi L, Lucifora B, Tracia L, et al. (2013) Cutaneous Rosai-Dorfmann Disease in Autistic Patient: Is there a Pathogenetic Correlation? J Clin Case Rep 3:312. doi:10.4172/2165-7920.1000312
Copyright: © 2013 Caglia P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Rosai-Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy, is a benign disorder of histiocyte proliferation that usually affects the lymph nodes. Purely Cutaneous Rosai-Dorfman Disease (CRDD) is a rare extranodal variant that is strictly limited to the skin. We report a patient with of cutaneous rosai-dorfman of the abdominal wall with a past medical history of autism spectrum disorders. Autism is surely a complex disease and the most prevailing opinion is that it is a neuro-immune disorder. Both the diseases are considered strictly correlated to the immune disorders and the immunodeficiency might play an important pathogenetic role. A brief review of the literature of CRDD is also provided.


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