Cutaneous Rosai-Dorfmann Disease in Autistic Patient: Is there a Pathogenetic Correlation?
|Caglia P*, Tracia A, Borzi L, Lucifora B, Tracia L, Spataro D and Amodeo C|
|Department of Surgical Sciences, Organ Transplantation and Advanced Technologies, Surgery Oncology, Unit University of Catania, Italy|
|Corresponding Author :||Caglia Pietro
Department of Surgical Sciences
Organ Transplantation and Advanced Technologies
Surgery Oncology, Unit University of Catania, Italy
|Received October 10, 2013; Accepted November 11, 2013; Published November 13, 2013|
|Citation: Caglia P, Tracia A, Borzi L, Lucifora B, Tracia L, et al. (2013) Cutaneous Rosai-Dorfmann Disease in Autistic Patient: Is there a Pathogenetic Correlation? J Clin Case Rep 3:312. doi:10.4172/2165-7920.1000312|
|Copyright: © 2013 Caglia P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
Rosai-Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy, is a benign disorder of histiocyte proliferation that usually affects the lymph nodes. Purely Cutaneous Rosai-Dorfman Disease (CRDD) is a rare extranodal variant that is strictly limited to the skin. We report a patient with of cutaneous rosai-dorfman of the abdominal wall with a past medical history of autism spectrum disorders. Autism is surely a complex disease and the most prevailing opinion is that it is a neuro-immune disorder. Both the diseases are considered strictly correlated to the immune disorders and the immunodeficiency might play an important pathogenetic role. A brief review of the literature of CRDD is also provided.