alexa Cytokines Induced Skin Adverse Reactions | OMICS International
ISSN: 2155-9554

Journal of Clinical & Experimental Dermatology Research
Open Access

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Research Article

Cytokines Induced Skin Adverse Reactions

Jun Zhang1#, Ling-He Meng1#, Li-Tao Zhang2* and Guang-Xin Yu2#

1Department of Dermatology, Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, China

2Tianjin Medical University, Tianjin, China

#Contributed equally to the paper

*Corresponding Author:
Li-Tao Zhang
Department of dermatology
Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital
354 Beima Road, Tianjin 300120, China
Tel: +86-22-27282109
Fax: +86-22-27285158
E-mail: [email protected]

Received date: October 10, 2013; Accepted date: January 02, 2014; Published date: January 09, 2014

Citation: Zhang J, Meng LH, Zhang LT, Yu GX (2014) Cytokines Induced Skin Adverse Reactions. J Clin Exp Dermatol Res 5:204. doi: 10.4172/2155-9554.1000204

Copyright: © 2014 Zhang J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Cutaneous adverse reaction is a common complication in association with the administration of cytokine products. Local inflammation reactions at the injection sites, widespread eruptions, exacerbation the primary autoimmune disorders and flu-like symptoms are frequently reported, besides, various rare side effects also have been observed. Though the exact mechanism is not clearly understood, the biological activities of cytokines in immunological reactions and impurities in biological products have been discussed.

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