alexa Cytotoxic Activity of Extracts/Fractions of Various Par
ISSN: 2161-1025

Translational Medicine
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Research Article

Cytotoxic Activity of Extracts/Fractions of Various Parts of Pistacia Integerrima Stewart

Ghias Uddin1*, Abdur Rauf1, Bina Shaheen Siddiqui2 and Haroon Khan3

1Institute of Chemical Sciences, University of Peshawar, Pakistan

2H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Pakistan

3Gandhara College of Pharmacy, Gandhara University, Peshawar, Pakistan

*Corresponding Author:
Ghias Uddin
Institute of Chemical Sciences
University of Peshawar
K.P.K Peshawar-25120, Pakistan
Tel: +92-91-9216652
Fax: +92-91-9216652
E-mail: [email protected], [email protected]

Received Date: September 23, 2013; Accepted Date: November 11, 2013; Published Date: November 13, 2013

Citation: Uddin G, Rauf A, Siddiqui BS, Khan H (2013) Cytotoxic Activity of Extracts/Fractions of Various Parts of Pistacia Integerrima Stewart. Transl Med 3:118. doi:10.4172/2161-1025.1000118

Copyright: © 2013 Uddin G, et al., This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

The aim of present study was to scrutinize cytotoxic activity of extracts/fractions of various parts of Pistacia integerrima Stewart in an established in-vitro brine shrimp cytotoxic assay. The extracts/fractions of different parts of the plant demonstrated profound cytotoxic effect against Artemia salina (Leach) shrimp larvae. Of the various parts of plant tested, galls accumulated most cytotoxic agents. Among the tested extracts/fractions, hexane was least cytotoxic and therefore indicated more polar nature of cytotoxic constituents. In conclusions, extracts/fractions of various parts of P. integerrima exhibited marked cytotoxic profile of more polar nature.

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