Cytotoxic Activity of Extracts/Fractions of Various Parts of Pistacia Integerrima Stewart
- *Corresponding Author:
- Ghias Uddin
Institute of Chemical Sciences
University of Peshawar
K.P.K Peshawar-25120, Pakistan
E-mail: [email protected], [email protected]
Received Date: September 23, 2013; Accepted Date: November 11, 2013; Published Date: November 13, 2013
Citation: Uddin G, Rauf A, Siddiqui BS, Khan H (2013) Cytotoxic Activity of Extracts/Fractions of Various Parts of Pistacia Integerrima Stewart. Transl Med 3:118. doi:10.4172/2161-1025.1000118
Copyright: © 2013 Uddin G, et al., This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The aim of present study was to scrutinize cytotoxic activity of extracts/fractions of various parts of Pistacia integerrima Stewart in an established in-vitro brine shrimp cytotoxic assay. The extracts/fractions of different parts of the plant demonstrated profound cytotoxic effect against Artemia salina (Leach) shrimp larvae. Of the various parts of plant tested, galls accumulated most cytotoxic agents. Among the tested extracts/fractions, hexane was least cytotoxic and therefore indicated more polar nature of cytotoxic constituents. In conclusions, extracts/fractions of various parts of P. integerrima exhibited marked cytotoxic profile of more polar nature.