alexa Cytotoxicity of Bismuth Compounds to Cultured Cancer Ce
ISSN: 2161-0525

Journal of Environmental & Analytical Toxicology
Open Access

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Short Communication

Cytotoxicity of Bismuth Compounds to Cultured Cancer Cells

Jun Kobayashi1*, Keiichi Ikeda2 and Hideo Sugiyama3

1Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, Tokyo, Japan

2Faculty of Pharmaceutical Sciences, Hokuriku University, Ishikawa, Japan

3Graduate School of Health Sciences, Matsumoto University, Nagano, Japan

*Corresponding Author:
Jun Kobayashi
School of Veterinary Nursing and Technology, Faculty of Veterinary Medicine
Nippon Veterinary and Life Science University, 1-7-1 Kyonan-cho, Musashino, Tokyo 180-8602, Japan
Tel: +81422314151
Fax: +81422332094
E-mail: [email protected]

Received Date: March 21, 2017; Accepted Date: April 26, 2017; Published Date: April 29, 2017

Citation: Kobayashi J, Ikeda K, Sugiyama H (2017) Cytotoxicity of Bismuth Compounds to Cultured Cancer Cells. J Environ Anal Toxicol 7:462. doi: 10.4172/2161-0525.1000462

Copyright: © 2017 Kobayashi J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Bismuth (Bi) is a ubiquitous metal, but its effects on human health are unknown. We examined the cytotoxicity of Bi compounds to cultured 8505C human thyroid cancer cells. Treatments of 0.05–0.1 mM of Bi subgallate and free gallic acid resulted in cell death in approximately 100% of cells.

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