Cytotoxicity of Bismuth Compounds to Cultured Cancer Cells
- *Corresponding Author:
- Jun Kobayashi
School of Veterinary Nursing and Technology, Faculty of Veterinary Medicine
Nippon Veterinary and Life Science University, 1-7-1 Kyonan-cho, Musashino, Tokyo 180-8602, Japan
E-mail: [email protected]
Received Date: March 21, 2017; Accepted Date: April 26, 2017; Published Date: April 29, 2017
Citation: Kobayashi J, Ikeda K, Sugiyama H (2017) Cytotoxicity of Bismuth Compounds to Cultured Cancer Cells. J Environ Anal Toxicol 7:462. doi: 10.4172/2161-0525.1000462
Copyright: © 2017 Kobayashi J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Bismuth (Bi) is a ubiquitous metal, but its effects on human health are unknown. We examined the cytotoxicity of Bi compounds to cultured 8505C human thyroid cancer cells. Treatments of 0.05–0.1 mM of Bi subgallate and free gallic acid resulted in cell death in approximately 100% of cells.