Deformable Dose Accumulation with Image Guided Radiotherapy for Final Dose Evaluation in Pelvic CasesYunfeng Cui1*, Jonathan W. Piper2, Amy S. Harrison1, Timothy N. Showalter1, Yan Yu1, James M. Galvin1 and Ying Xiao1
- Corresponding Author:
- Yunfeng Cui
Division of Medical Physics
Dept. of Radiation Oncology
Thomas Jefferson University Hospital
E-mail: [email protected]
Received Date: November 20, 2011; Accepted Date: November 22, 2011; Published Date: November 25, 2011
Citation: Cui Y, Piper JW, Harrison AS, Showalter TN, Yu Y, et al. (2011) Deformable Dose Accumulation with Image Guided Radiotherapy for Final Dose Evaluation in Pelvic Cases. J Nucl Med Radiat Ther S3:e001. doi:10.4172/2155-9619.S3-e001
Copyright: © 2011 Cui Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This study aims at a method that employs deformable dose accumulation for the evaluation of the results of intensity-modulated radiation therapy (IMRT) in pelvic cases. Each fraction dose was derived from the planning dose through rigid transformation accounting for setup corrections. Daily cone-beam CT (CBCT) images were used to deform the daily fraction dose to a reference geometry, which in our study was the first fraction geometry. A commercial software system, MIMvista, was used to perform deformable image registration, dose deformation, and dose accumulation. The differences in distributions of accumulated dose and planned dose were observed. The application of deformable dose accumulation is particularly useful in final accumulated dose evaluation throughout radiotherapy treatment, especially for the cases where there are significant deformations of planning target volume (PTV) and organs at risk (OARs).