alexa Delivery Techniques in Gene Therapy: A Brief Overview
ISSN: 2161-0398

Journal of Physical Chemistry & Biophysics
Open Access

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Review Article

Delivery Techniques in Gene Therapy: A Brief Overview

Daniel Lee John Bunker*
Department of Surgery, Launceston General Hospital, Launceston, Tasmania 7250, Australia
Corresponding Author : Daniel Lee John Bunker, MBBS (Hons)
BE Aero(space) Hons I, Univeristy Medal
Department of Surgery, Launceston General Hospital
Launceston, Tasmania 7250, Australia
Tel: +61439928732
E-mail: [email protected]
Received May 02, 2014; Accepted May 29, 2014; Published May 31, 2014
Citation: Bunker DLJ (2014) Delivery Techniques in Gene Therapy: A Brief Overview. J Phys Chem Biophys 4:147. doi:10.4172/2161-0398.1000147
Copyright: © 2014 Bunker DLJ. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

The use of gene therapy is rapidly gaining ground in the field of immunotherapy and the correction of monogenetic disorders. An ongoing challenge to the successful implementation of gene therapy to human subjects remains safe and efficient transfer of the plasmid to the host. Strategies for gene transfer include the use of viral vectors or synesthetic transfection systems incorporating physical, chemical, or electrical methods. While viral vectors remain the standard for transduction efficiency, synthetic systems offer potential safety advantages from an immunological perspective.

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