alexa Depressive Symptoms Prior to and after Incident Cardiovascular Disease and Long-term Survival A population-based Study of Older Persons
ISSN: 2167-1044

Journal of Depression and Anxiety
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Depressive Symptoms Prior to and after Incident Cardiovascular Disease and Long-term Survival A population-based Study of Older Persons

Rosanne Freak-Poli1,2*, Arfan Ikram M1,3,4, Oscar H Franco1, Albert Hofman1,5 and Henning Tiemeier1,6,7

1Department of Epidemiology, Erasmus Medical Centre, Rotterdam, The Netherlands

2Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia

3Department of Neurology, Erasmus Medical Centre, Rotterdam, The Netherlands

4Department of Radiology, Erasmus Medical Centre, Rotterdam, The Netherlands

5Department of Epidemiology, Harvard University, MA 02138, USA

6Department of Child and Adolescent Psychiatry, Erasmus Medical Centre, The Netherlands

7Department of Psychiatry, Erasmus Medical Centre, The Netherlands

*Corresponding Author:
Rosanne Freak-Poli
Department of Epidemiology
Erasmus University Medical Centre
The Netherlands
Tel: +31 (0)107038490
E-mail: [email protected]

Received Date: February 11, 2017; Accepted Date: February 20, 2017; Published Date: February 23, 2017

Citation: Freak-Poli R, Arfan Ikram M, Franco OH, Hofman A, Tiemeier H (2017) Depressive Symptoms Prior to and after Incident Cardiovascular Disease and Longterm Survival A population-based Study of Older Persons. J Depress Anxiety 6:270. doi: 10.4172/2167-1044.1000270

Copyright: © 2017 Freak-Poli R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Background: Depression after a CVD event is associated with increased mortality. However, little is known about how pre-existing depression affects survival after CVD incidence.

Aim: To evaluate whether depressive symptoms measured preceding first incident CVD (pre-CVD), as well as measured after CVD (post-CVD), affect survival.

Methods: From the Rotterdam Study, 6,932 persons aged 55+ and free of dementia and CVD completed the Center for Epidemiological Studies Depression (CES-D) scale every 4 to 5 years from 1993. CES-D subdomains were positive affect, negative affect, somatic symptoms and interpersonal affect. Persons were followed for mortality and CVD, defined as incident stroke, heart failure and coronary heart disease (CHD).

Results: During 15-year follow-up, 22% of participants suffered their first incident CVD. Depressive symptoms measured ≈3 years prior to first incident CVD were not associated with mortality after adjustment for smoking status and physical function (HR per 10-point score: 1.04, 95%CI: 0.97-1.10). Higher pre-CHD somatic symptoms were associated with greater CHD mortality and higher pre-stroke positive affect was associated with less stroke mortality. After first incident CVD, depressive symptoms increased. Higher depressive symptoms measured after CVD was associated with an increased risk for mortality (HR: 1.09, 95%CI: 1.00, 1.19). Higher post-CVD positive affect was protective of both all-cause and CVD mortality.

Conclusion: During 15-years follow-up in community-dwelling older adults, the relation between higher depressive symptoms measured before first incident CVD and mortality was not independent of health status. In contrast, higher depressive symptoms measured after CVD was associated with an increased risk for mortality.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords