alexa Dermatomyositis: A Retrospective Study of Sixteen Cases
ISSN: 2155-9554

Journal of Clinical & Experimental Dermatology Research
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Research Article

Dermatomyositis: A Retrospective Study of Sixteen Cases

Gbéry Ildevert Patrice, Ecra Elidjé Joseph*, Kassi Komenan Ahogo Kouadio, Celestin, Kouassi Kouamé Alexandre, Kouassi Yao Isidore, Sangaré Abdoulaye and Yoboué Yao Pauline
Department of Dermatology and Infectiology, Training and Research unit of Medical Sciences, University of Felix Houphouët Boigny, Abidjan, Republic of Côte d’Ivoire
Corresponding Author : Ecra Elidjé Joseph, Professor
Department of Dermatology and Infectiology
Training and Research unit of Medical Sciences
University of Felix Houphouët Boigny
Abidjan, Republic of Côte d’Ivoire
Tel: 225-07840978
E-mail: [email protected]
Received: December 05, 2015 Accepted: January 18, 2016 Published: January 22, 2016
Citation: Patrice GI, Joseph EE, Ahogo Kouadio KK, Celestin, Alexandre KK, et al. (2015) Dermatomyositis: A Retrospective Study of Sixteen Cases. J Clin Exp Dermatol Res 7:321. doi:10.4172/2155-9554.1000321
Copyright: © 2015 Patrice GI, et al. This is an open-access article distributed under the terms of the Creative Co mmons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Introduction: Dermatomyositis is an inflammatory multisystemic disease characterized by muscle weakness with a characteristic and pathognomonic cutaneous eruption. Our purpose was to describe the common cutaneous, extra-cutaneous features and course of dermatomyositis in our institution. Method: In this retrospective study we reviewed the medical data of dermatomyositis registered cases in dermatology department at Treichville teaching hospital in Côte d'ivoire from 2004 to 2013. Diagnosis was assessed for each case using the Bohan and Peter criteria for dermatomyositis. Result: Sixteen cases which fulfilled at least three out of four of the Bohan and Peter criteria for dermatomyositis were analysed. Prevalence was 15.3 for 10000 consulting patients. The delay to establish the diagnosis after the onset of the disease was 4 months. The average age of patients was 39 years. The sex ratio was 1.2. Features were: hyperpigmentation of sun exposed sites in 100% of cases, symmetric erythema in 93.7% of the cases, facial oedema in 56.2% of the cases, poïkilodermatous lesions in 25% of the cases. Telangiectasia was noted in 6.2% of the cases. The average delay for occurrence of muscular symptoms after the onset of cutaneous symptoms was 1 month. The longest delay was 4 months. All cases had at least proximal muscles weakness. Three cases representing 18.7% of cases displayed oesophageal .muscles involvement. Muscular biopsy analysis performed in 10 cases that represent 62.5% of cases was specific in 4 cases (40%) and not in 6 cases (60%). Electromyogram was performed in 75% of cases and displayed myogenic deficit in all of them. Serum LDH level has been abnormal in all cases. Whereas serum CPK level has been abnormal in 87.5% of the cases. Two cases representing 12.5% of the cases had interstitial pneumonia and pericarditis. In an average period follow-up of 12 months death occurred in 6.2% of the cases and invalidity was constant. We used oral prednisone in 93.7% of cases. The maximal dose useful to induce remission was 60 mg of prednisone a day. The minimal dose useful for remission control was 10 mg a day. The average delay for partial remission was 10 days. Relapse occurred in all cases when decreasing doses of prednisone. Conclusion: We confirm that dermatomyositis is an uncommon disease. Our cases of dermatomyositis are relatively younger than those classically described. There was no sex predominance.

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