alexa Dermatophyte Growth in Glabrous Skin Dermatophytoses of
ISSN: 2168-9784

Journal of Medical Diagnostic Methods
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Review Article

Dermatophyte Growth in Glabrous Skin Dermatophytoses of Immuno Compromised Hosts

Gérald E. Piérard1,*, Claudine Piérard-Franchimont1,2, Trinh Hermanns-Lê2, Jean-François Hermanns2 and Philippe Delvenne2,3
1Laboratory of skin Bioengineering and Imaging, Department of Clinical Sciences, University of Liège, 4000 Liège, Belgium
2Department of Dermatopathology, Unilab Lg, University Hospital of Liège, 4000 Liège, Belgium
3Department of Pathology, Unilab Lg, University Hospital of Liège, 4000 Liège, Belgium
Corresponding Author : Gérald E. Piérard
Laboratory of Skin Bioengineering and Imaging
Department of Clinical Sciences, University of Liège
B-4000 Liège, Belgium
Tel: +32 4 366248
Fax: +32 4 3662976
E-mail: [email protected]
Received: November 05, 2015 Accepted: December 07, 2015 Published: December 14, 2015
Citation: Piérard GE, Piérard-Franchimont C, Hermanns-Lê T, Hermanns JF, Delvenne P (2015) Dermatophyte Growth in Glabrous Skin Dermatophytoses of Immuno Compromised Hosts. J Med Diagn Meth 4:1000186. doi: 10.4172/2168-9784.1000.186
Copyright: © 2015 Pierard GE, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Infections remain the most common immediate causes of morbidity in immune compromised hosts. The abated host defences are responsible for an increased susceptibility to various uncommon and opportunistic pathogens, and to a lowered host inflammatory response. Skin lesions develop in up to a third of infections in these patients, and they possibly represent the initial step of a systemic illness. Superficial mycoses are occasionally present under unusual atypical presentations. The resulting clinical infections are at times difficult to diagnose. Some of them are recalcitrant to common conventional therapies. The broad scope of cutaneous manifestations of infections in compromised patients are classified based on four presumed underlying physio-pathologic mechanisms, and on the vast array of potential pathogens so far identified. For mild superficial infections, prompt adequate therapy decreases morbidity and lessens the risk of complications. For more severe involvement, early detection of opportunistic fungal infections helps increasing both the cure and survival rates.

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