alexa DETECHIP®: An Improved Molecular Sensing Array
ISSN: 2157-7145

Journal of Forensic Research
Open Access

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Research Article

DETECHIP®: An Improved Molecular Sensing Array

Marcus Lyon1, Jordan Groathouse1, Jordan Beaber1, Laura M. Turner1, Kerry A. Rouhier2, Mark V. Wilson1, David J. Symonsbergen3, Sharmin M. Sikich1*and Andrea E. Holmes1*

1Doane College, Department of Chemistry, 1014 Boswell Avenue, Crete, NE 68333, USA

2Kenyon College, Department of Chemistry, 200 N. College, Gambier, OH 43022, USA

3NOVEL Chemical Solutions, 1155 E. Hwy 33, Crete, NE 68333, USA

*Corresponding Authors:
Dr. Andrea E. Holmes, PhD
Assistant Professor of Chemistry
Doane College, 1014 Boswell Ave. Crete
NE 68333, USA
Tel: (402)826-6762
Fax: (402)826-8278
E-mail: [email protected]
 
Dr. Sharmin M. Sikich, PhD
Department of Chemistry
Doane College, 1014 Boswell Ave. Crete
NE 68333
E-mail: [email protected]

Received date: April 13, 2011; Accepted date: May 15, 2011; Published date: May 17, 2011

Citation: Lyon M, Groathouse J, Beaber J, Turner LM, Rouhier KA, et al. (2011) DETECHIP®: An Improved Molecular Sensing Array. J Forensic Res 2:126. doi:10.4172/2157-7145.1000126

Copyright: © 2011 Lyon M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

DETECHIP ® is a novel, highly selective and sensitive molecular sensor array producing color and fluorescence changes in the presence of many small molecules or analytes. This technology utilizes an array of eight sensors in two types of buffers that are dispensed in a 96-well plate. Color and fluorescent changes in the presence of analytes are recorded as a 32 digit binary code that is able to discriminate many substances. The current application is dedicated to testing narcotics such as cocaine, tetrahydrocannabinol (THC) from marijuana, as well as date- rape and club drugs such as flunitrazepam, gamma-hydroxybutyric acid (GHB), and methamphetamine, to name a few. Shown to be a contactless, portable, and inexpensive optical detection system, DETECHIP ® can detect many substances and therefore can be used where a high degree of preliminary diagnostics is needed.Besides narcotics, DETECHIP ® is able to detect and discriminate over-the-counter medications, trinitrotoluene (TNT), pesticides, food spoilage metabolites, and narcotics laced with cutting agents. DETECHIP ® offers possibilities for a simple, sensitive, selective, and affordable alternative to costly immunoassays.

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