alexa Determinants of Success in EGFR Mutation Status Analysi
ISSN: 2165-7920

Journal of Clinical Case Reports
Open Access

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Case Report

Determinants of Success in EGFR Mutation Status Analysis in EBUS-TBNA Specimens: The Role of PET-CT

Alvin Hon Man Tung*, Jenny Chun Li Ngai, Susanna So Shan Ng, Kin Wang To and Fanny Wai San Ko
Department of Medicine and Therapeutics, Prince of Wales Hospital, Shatin, Hong Kong
Corresponding Author : Alvin Hon-Man Tung
Department of Medicine and Therapeutics
Chinese University of Hong Kong
Shatin, Hong Kong
Tel: (852) 2632 3128
Fax: (852) 2649 9957
E-mail: [email protected]
Received May 23, 2014; Accepted July 23, 2014; Published July 25, 2014
Citation: Tung AHM, Ngai JCL, Ng SSS, To KW, Ko FWS (2014) Determinants of Success in EGFR Mutation Status Analysis in EBUS-TBNA Specimens: The Role of PET-CT. J Clin Case Rep 4:395 doi:10.4172/2165-7920.1000395
Copyright: © 2014 Tung AHM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


In our Chinese cohort of 27 Non-Small Cell Lung Cancer (NSCLC) patients with mediastinal nodal involvement who underwent EBUS-TBNA, we showed no role of SUV from PET-CT scans in determining EGFR mutation status. Nonetheless, we showed that patients with high SUV (>9.6) as well as number of passes could predict inadequacy of cellular material in obtaining EGFR mutation status in EBUS-TBNA.

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