Determination of 2-Mercaptoethanol by Potentiometric Titration with Mercury (II) Chloride
Ali Rasool Mahmood Albakaa*
Department of Pharmaceutical Chemistry, College of Pharmacy, University of Al-Mustansiriyah, Baghdad, Iraq
- Corresponding Author:
- Ali Rasool Mahmood Albakaa
Department of Pharmaceutical Chemistry
College of Pharmacy, University of Al-Mustansiriyah, Baghdad, Iraq
E-mail: [email protected]
Received date: May 30, 2016; Accepted date: July 19, 2016; Published date: July 26, 2016
Citation: Albakaa ARM (2016) Determination of 2-Mercaptoethanol by Potentiometric Titration with Mercury (II) Chloride. Chem Sci J 7:138. doi:10.4172/2150-3494.1000138
Copyright: © 2016 Albakaa ARM. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
A new, direct, rapid, simple, sensitive and accurate method for the determination of 2-Mercaptoethanol (Quick facts) or Mercury(II); The method is based on the using mercury (II) chloride solution as titrant (or reverse) in potentiometric titration depending on the first and second derivative differential procedure was used for all titrations; The method is suitable for the assay of 2-ME in micro amounts at a wide range of mass (15626.6-7.8133 μg) in 80 mL; The equivalence point is marked by a sharp peak in all instances and molar ratio of (Hg2+: 2-ME) at inflection point (1:2). Accurate and precise results were obtained with an average error % of (0.1333-0.5667%) and a Relative Standard Deviation of (0.70499-0.1957%) respectively.