alexa Diagnosis of Subcutaneous Metastatic Deposits by Fine Needle Aspiration
ISSN: 2157-7099

Journal of Cytology & Histology
Open Access

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Research Article

Diagnosis of Subcutaneous Metastatic Deposits by Fine Needle Aspiration

Bita Geramizadeh1,2*, Saeed Marzban3, Nazanin Karamifar1, Navid Omidifar1, Mansooreh Shokripour1 and Mohammad Reza Mokhtareh1

1Department of Pathology, Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

2Transplant Research Center, Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

3Department of Plastic Surgery, Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

*Corresponding Author:
Bita Geramizadeh
Department of Pathology
Transplant Research Center
Shiraz University of Medical Sciences
Shiraz, Iran, PO BOX: 71345-1864
Tel: 0098-711-6474331
E-mail: [email protected]

Received Date: July 04, 2012; Accepted Date: July 24, 2012; Published Date: July 26, 2012

Citation: Geramizadeh B, Marzban S, Karamifar N, Omidifar N, Shokripour M, et al. (2012) Diagnosis of Subcutaneous Metastatic Deposits by Fine Needle Aspiration. J Cytol Histol 3:151. doi:10.4172/2157-7099.1000151

Copyright: © 2012 Geramizadeh B, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Objectives: Subcutaneous tissue is an uncommon site of metastasis. Overall it can be seen in 0.8-4% of the malignancies. Fine Needle Aspiration Cytology (FNAC) is a method for the diagnosis of subcutaneous metastasis and to exclude other differential diagnoses such as primary cutaneous tumors or inflammatory process. In this study we want to report our experience with Fine Needle Aspiration (FNA) of subcutaneous metastasis in 25 patients with known malignancy. Study design: During 3 years, among more than 10000 cytology cases, we had 25 patients with different types of malignancy who were referred with subcutaneous nodules. FNA was performed. Results: In these 25 patients, there were 15 males and 10 female patients (22-80 years of age). Most common malignancy was breast cancer and the most common site of metastasis was subcutaneous tissue of chest wall. FNAC was 100% accurate for the diagnosis of subcutaneous metastasis. There were no false positive and false negative cases. Discussion and conclusion: FNAC is an accurate, noninvasive and fast method for the diagnosis of subcutaneous metastasis in the patients with a known malignancy without any complication.


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