alexa Differentially loaded Radiostereometric Analysis (DLRSA) in Torsion Adds Essential Information in Diaphyseal Bone Healing: the Example of a Tibial Osteotomy
ISSN: 2155-9538

Journal of Bioengineering & Biomedical Science
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Differentially loaded Radiostereometric Analysis (DLRSA) in Torsion Adds Essential Information in Diaphyseal Bone Healing: the Example of a Tibial Osteotomy

M.J. Chehade1,2, I.A. Vakaci2, S.A. Callary1,2, D.M. Findlay2 and L.B. Solomon1,2

1Department of Orthopaedics and Trauma, Royal Adelaide Hospital

2Discipline of Orthopaedics and Trauma, University of Adelaide, Adelaide, Australia

*Corresponding Author:
Mellick Chehade
Associate Professor
Level 4 Bice Building
Department of Orthopaedics and Trauma
Royal Adelaide Hospital
North Terrace, Adelaide, Australia 5000
Tel: 61 8 82225661
Fax: 61 8 8232 3065
E-mail: [email protected]

Received Date: November 03, 2011; Accepted Date: November 21, 2011; Published Date: November 22, 2011

Citation: Chehade MJ, Vakaci IA, Callary SA, Findlay DM, Solomon LB (2011) Differentially loaded Radiostereometric Analysis (DLRSA) in Torsion Adds Essential Information in Diaphyseal Bone Healing: the Example of a Tibial Osteotomy. J Bioeng Biomed Sci S1:004. doi:10.4172/2155-9538.S1-004

Copyright: © 2011 Chehade MJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Background Clinical assessment and conventional imaging, which are currently used to monitor fracture healing, do not provide information on the mechanical properties of the healing construct. This limits their use in patient management decisions. Differentially loaded radiostereometric analysis (DLRSA) is a technique developed to assess the mechanical properties of healing fractures in vivo. DLRSA measures the relative micromotion of tantalum beads inserted into bone fracture fragments in response to load across the fracture site. To date, these loads have been applied axially, although in fractures fixed with devices which are highly resistant to axial loads, such as locked intramedullary nails, torsional testing may be more sensitive to healing. The aim of this study was to establish a method to investigate DLRSA using torsional loading for clinical application.

Methods A device was designed and built to apply torsional loads to the tibia. The test case was an oblique plain corrective osteotomy of a tibial diaphysis stabilized with an intramedullary nail and with tantalum beads inserted into the two adjacent bone segments. Post surgical examinations were made at 2 weeks, 2, 4, and 6 months as well as 1 and 2 years. Healing was monitored with the use of plain film radiographs, computed tomography (CT) and DLRSA. Axial loads of 30kg and an external torsion of 5Nm were applied during DLRSA examinations and the resultant displacement and stiffness were calculated.

Results Torsional DLRSA demonstrated progressive changes in angular displacements and torsional stiffness consistent with the fracture healing observed by CT. By contrast, axial DLRSA was not informative and was more reflective of the stability of the fixation than healing bone.

Conclusion The addition of torsional assessments to DLRSA provides an important investigative option in assessing the biomechanical properties of bone healing in vivo .


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version