Differentiation of Tumefactive Demyelinating Lesions from Metastatic Brain Disease with FDG PET-CT: A Case ReportKresimir Dolic1*, Ivica Bilic2, Ante Buca1, Darijo Radovic3 and Marina Titlic2
- Corresponding Author:
- Kresimir Dolic, MD, PhD
Clinical Department of Interventional and Diagnostic Radiology
University Hospital Split, Spinciceva 1, 21000 Split, Croatia
Tel: +385 21 556-243
E-mail: [email protected]
Received date: April 23, 2014; Accepted date: May 27, 2014; Published date: May 30, 2014
Citation: Dolic K, Bilic I, Buca A, Radovic D, and Titlic M (2014) Differentiation of Tumefactive Demyelinating Lesions from Metastatic Brain Disease with FDG PET-CT: A Case Report. J Mult Scler 1:108. doi:10.4172/2376-0389.1000108
Copyright: © 2014 Dolic K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Tumefactive demyelinating brain disease can pose a diagnostic challenge in patients without a pre-existing diagnosis of multiple sclerosis by mimicking intra-cranial neoplasms, infarction, as well as infections. Choosing when to biopsy a tumefactive lesion to exclude alternative pathology can be difficult. Here we report a case of a 44 year old female patient without a previous history of multiple sclerosis who presented with two brain lesions mimicking metastatic brain disease which pose a serious diagnostic dilemma. FDG PET CT and follow up magnetic resonance imaging (MRI) helped to rule out tumor etiology of those lesions and spared patient from invasive procedures such as biopsy or radiotherapy.