alexa Diffuse Parenchymal Lung Disease-Diagnostic Approach by Radiology and Histopathology
ISSN: 2157-7099

Journal of Cytology & Histology
Open Access

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Research Article

Diffuse Parenchymal Lung Disease-Diagnostic Approach by Radiology and Histopathology

Aastha Gupta1, Shaista M Vasenwala1, Kafil Akhtar1*, Rakesh Bhargava2, Ibne Ahmad3 and Veena Maheshwari1

1Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India

2T.B Chest & Respiratory Disorder, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India

3Radio-diagnosis, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India

*Corresponding Author:
Kafil Akhtar
Department of Pathology
Jawaharlal Nehru Medical College
Aligarh Muslim University, Aligarh
Uttar Pradesh, India
E-mail: [email protected]

Received Date: August 16, 2011; Accepted Date: February 07, 2012; Published Date: February 10, 2012

Citation: Gupta A, Vasenwala SM, Akhtar K, Bhargava R, Ahmad I, et al. (2012) Diffuse Parenchymal Lung Disease-Diagnostic Approach by Radiology and Histopathology. J Cytol Histol 3:132. doi:10.4172/2157-7099.1000132

Copyright: © 2012 Gupta A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Aims and objective:This study aims at evaluating the patients of diffuse parenchymal lung disease (DPLD), by comparing radiological and cyto-histopathological findings to determine the importance of histopathology in the diagnosis of DPLD.

Materials and methods:Seventy patients with chief complaints of dyspnoea & cough and bilateral diffuse shadows on chest radiography were selected. High resolution computed tomography (HRCT) and bronchoscopy was done for further assessment.

Results:Out of70 patients, 44 were finally diagnosed on the basis of bronchoscopic findings, as usual interstitial pneumonia (UIP) 24 cases (54.5%) and as non UIP in 20 cases (45.5%). Two cases of UIP additionally suffered from bronchogenic carcinoma.

Conclusion:A combination of clinical, radiological, cytological and histological findings is necessary to evaluate the cases of DPLD and transbronchial needle biopsy (TBNB) gives a definitive edge over other diagnostic measures.

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