Diketopiperazines Produced by an Bacillus Species Inhibits Vibrio Parahaemolyticus
- *Corresponding Author:
- Dr.Yanett Leyton
Bioinnovation Center, Microbial Ecology Laboratory
Faculty of Marine Resources
Universidad de Antofagasta, Antofagasta. Chile
E-mail: [email protected]
Received Date: June 20, 2012; Accepted Date: August 01, 2012; Published Date: August 10, 2012
Citation: Leyton Y, Borquez J, Darias J, Cueto M, Díaz-Marrero AR, et al. (2012) Diketopiperazines Produced by an Bacillus Species Inhibits Vibrio parahaemolyticus. J Aquacult Res Dev 3:144. doi:10.4172/2155-9546.1000144
Copyright: © 2012 Sarkar A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
In this work organic products were isolated and identified from a marine Bacillus sp. which presented growth inhibition of the pandemic strain of V.
. The inhibitory products were extracted and characterized by spectroscopic and
techniques. Purification of the active products revealed five different diketopiperazines, which were compared with standards from high-performance liquid chromatography (HPLC). Although the diketopiperazines is not a finding of a new metabolite, the interested point or novelity of this work is the ability of diketopiperazines to inhibit the growth of pandemic strain of V. parahaemolyticus. We suggest the possibility of using this compound to reduce the growth and control the proliferation of pathogenic clones of V.parahaemolyticus that cause several problems in aquaculture industry.