alexa Disseminated Tuberculosis among Adult Patients Admitted
ISSN: 2161-1068

Mycobacterial Diseases
Open Access

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Research Article

Disseminated Tuberculosis among Adult Patients Admitted to Hamad General Hospital, Qatar: A Five Year Hospital Based Study

Fahmi Yousef Khan1, Khalid Dosa2, Amr Fuad1, Walid Ibrahim1, Ahmed Alaini3, Lubna Osman1, Mohamed Albadri4 and Mohamed Abdel Daem Yassin5

1Department of Medicine, Hamad General Hospital, Doha, Qatar

2Department of Medicine, Infectious disease division, Hamad General Hospital, Doha, Qatar

3Department of Medicine, Pulmonary disease division, Hamad General Hospital, Doha, Qatar

4Department of Medicine, Gastroenterology disease division, Hamad General Hospital, Doha, Qatar

5Hematology division, AL Amal Hospital, Doha, Qatar

Corresponding Author:
Khan FY
Department of Medicine
Hamad General Hospital, Doha-Qatar 3050
Tel: +97444879228
Fax: +97444879228
E-mail: [email protected]

Received date: April 23, 2016; Accepted date: June 15, 2016; Published date: June 22, 2016

Citation: Khan FY, Dosa K, Fuad A, Ibrahim W, Alaini A, et al. (2016) Disseminated Tuberculosis among Adult Patients Admitted to Hamad General Hospital, Qatar: A Five Year Hospital Based Study . Mycobact Dis 6:212. doi:10.4172/2161-1068.1000212

Copyright: © 2016 Khan FY, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Objectives: To describe the demographic, clinical features, diagnostic and procedure results, organ involvement and outcomes in patients with disseminated tuberculosis (TB).

Patients and methods: This retrospective observational study was conducted at Hamad general hospital in Qatar. It involved all patients 15 years of age or older who were admitted to Hamad general hospital with disseminated TB from January 1, 2006 to December 31, 2010.

Results: We enrolled 100 patients. There were 74 (74%) males and the mean age (±SD) of patients was 31.3±12.2. The most common presenting symptom was fever (95%). Fifteen (15%) patients had other underlying medical conditions; the most common being diabetes mellitus 7 (7%), while two patients had human immunodeficiency virus (HIV) infection. The tuberculin skin test was positive in 42 (42%) patients. Sputum and gastric lavage examination were performed in 84 (84%) and 9 (9%) patients respectively while bronchoscopy was performed on 32 (32%) cases. Most patients 94 (94%) completed their treatment in Qatar whereas (3%) left the country before completion. The in-hospital mortality rate was 3% (3 patients). Systemic corticosteroids were prescribed for 36 (36%) cases and 15 patients had complications, the most being tuberculoma 9/23 (39.1%). Drug toxicity was noted in 17 (17%) patients, including hepatitis, optic neuritis and hyperurecemia. Only presence of underlying medical conditions was found to be an independent predictor of mortality.

Conclusions: Disseminated TB has a non-specific clinical picture, gives rise to high morbidity

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