alexa Diversity of Nutrient Content in Grains - A Pilot Metabolomics Analysis
ISSN: 2155-9600

Journal of Nutrition & Food Sciences
Open Access

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Research Article

Diversity of Nutrient Content in Grains - A Pilot Metabolomics Analysis

Douglas P. Lee1, Danny Alexander1 and Satya S. Jonnalgadda2*

1Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA

2General Mills Bell Institute of Health and Nutrition, 9000 Plymouth Avenue North, Golden Valley, MN 55427, USA

*Corresponding Author:
Satya S. Jonnalagadda
General Mills Bell Institute of Health and Nutrition
9000 Plymouth Avenue North, Golden Valley, MN 55427, USA
Tel: +1763-764-3939
Fax: +1-763-764-3262
E-mail: [email protected]

Received Date: January 07, 2013; Accepted Date: January 23, 2013; Published Date: January 25, 2013

Citation: Lee DP, Alexander D, Jonnalgadda SS (2013) Diversity of Nutrient Content in Grains - A Pilot Metabolomics Analysis. J Nutr Food Sci 3:191. doi: 10.4172/2155-9600.1000191

Copyright: © 2013 Lee DP, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Grains are a major food source providing many essential nutrients. The objective of this work was to determine the biochemical (<1,500 Da) composition of selected grains and grain fractions. We hypothesized that the nutrient composition of grains is not only dependent on the grain type, but also influenced by the milling process to generate individual fractions. Whole grain corn, oat, and wheat were milled and separated into bran and flour/meal fractions. The biochemical composition of the whole grains and their subcomponents were determined by untargeted metabolomic profiling on methanol extracts. This global analysis identified 325 biochemicals, belonging to diverse nutrient categories including carbohydrates, antioxidant, vitamins and amino acids. Many of the metabolites were significantly different between the grain types and grain fractions; statistical analysis showed clear differences in the biochemical composition of corn, oat, and wheat grains. Principle component analysis showed that whole wheat flour  and whole oat flour were not distinguishable from their respective grains, while corn meal could be distinguished from the corn grain kernel. Many of these nutrients were decreased in the bran fractions upon processing. This
preliminary study provides a glimpse into distinct profiles of different grains and their fractions, which can  potentially have an impact on nutrition, health and other parameters. Further research is needed to better understand the health benefits of these compounds in individual grains and grain fractions. The use of metabolomics techniques to better understand the profiles of foods not only can help understand their role in improving their health, but also their impact on food product quality, food safety and other parameters.

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