alexa Does the Role of Angiogenesis Play a Role in Atherosclerosis and Plaque Instability? | OMICS International | Abstract
ISSN: 2161-0940

Anatomy & Physiology: Current Research
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Review Article

Does the Role of Angiogenesis Play a Role in Atherosclerosis and Plaque Instability?

Patel A*

Department of Medicine, King's College, London, UK

*Corresponding Author:
Amisha Patel
Department of Medicine, King's College, London, UK
Tel: 07904 922 814
E-mail: [email protected]

Received date: April 21, 2014; Accepted date: June 03, 2014; Published date: June 05, 2014

Citation: Patel A (2014) Does the Role of Angiogenesis play a Role in Atherosclerosis and Plaque Instability?. Anat Physiol 4:147. doi: 10.4172/2161-0940.1000147

Copyright: © 2014 Patel A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Atherosclerosis is an inflammatory vascular disease which begins as fatty streaks underlining the endothelium of large artery walls, usually coronary or carotid. It consists of endothelial dysfunction, the accumulation of lipid and cholesterol in the intima from a young age and the recruitment of inflammatory cells to sites of damage in the artery wall. The disease progresses through several stages, eventually resulting in the formation of a cholesterol rich plaque. The role of angiogenesis in atherosclerosis has been of growing interest over the last 20 years since experimental studies have not been able to support a causal relation. Angiogenesis involves hyperplasia of the vasa vasorum in the early stages of atherosclerosis which is thought to be angiogenesis independent, followed by intimal neovascularization in the late angiogenesis dependent stages of the disease. Angiogenesis increases the supply of oxygen and nutrients to the artery wall and supports initial plaque growth. Once the atherosclerotic plaque develops, intimal angiogenesis is thought to contribute to characteristics of an unstable plaque such as fibrous cap thinning, a cholesterol rich necrotic core, excess infiltration of inflammatory cells, plaque hemorrhage and the increased risk of plaque rupture. This account discusses the evidence behind the role of angiogenesis in atherosclerosis and plaque instability.


Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A


[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


porn sex

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

Gaziantep Escort

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A


[email protected]

1-702-714-7001Extn: 9037


James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

mp3 indir

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals


Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T


[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7