alexa Does Visfatin Predict Cardiovascular Complications in Metabolic Syndrome Patients? | OMICS International
ISSN: 2161-1017

Endocrinology & Metabolic Syndrome
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Research Article

Does Visfatin Predict Cardiovascular Complications in Metabolic Syndrome Patients?

Alexander Berezin*

Department of Internal Medicine, State Medical University, Mayakovsky av, Ukraine

*Corresponding Author:
Alexander Berezin
Department of Internal Medicine
State Medical University
Mayakovsky av-69035, Ukraine
Tel: +38 061 2894585
Fax: +38 0612894585
E-mail: [email protected]

Received date: July 23, 2015 Accepted date: January 02, 2016 Published date: January 08, 2016

Citation: Berezin A (2016) Does Visfatin Predict Cardiovascular Complications in Metabolic Syndrome Patients?. Endocrinol Metab Syndr 5:224. doi:10.4172/2161-1017.1000224

Copyright: © 2016 Berezin A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Vistafin is insulin-mimicking adipocytokine secreted from visceral adipose tissue, which plays an essential role in a number of biological processes affected glucose uptake regulation, inflammation, immunity, insulin resistance, vascular calcification, capillary tube formation, endothelial cell function and angiogenesis. Circulating level of visfatin exhibits to be a sufficiently increased in MetS and Type 2 Diabetes Mellitus (T2DM) patients compared with healthy individuals. Several clinical studies have shown that serum vitafin may predict Cardiovascular (CV) disease and CV events in MetS and T2DM patients. The review summarizes the various aspects of the role of vistafin as biomarker of MetS compared with commonly used biomarkers, i.e. adiponectin, leptin, resistin, apelin. In future more investigations are needed to better understand the role of vistafin in dysmetabolic-related disease and its ability to predict CV complications in these patient population

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