alexa Dont Forget the Skin: 4 Common Dermatologic Manifestati

Journal of Oncology Medicine & Practice
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Dont Forget the Skin: 4 Common Dermatologic Manifestations of Internal Malignancy

Reid A Waldman and Steven D Waldman*

University of Missouri School of Medicine, Missouri, USA

*Corresponding Author:
Steven D Waldman, MD, JD, MBA
Clinical Professor of Anesthesiology
University of Missouri School of Medicine, Missouri, USA
Tel: 913-327-5999
E-mail: [email protected]

Received date September 16, 2015; Accepted date October 03, 2015; Published date October 06, 2015

Citation: Waldman RA, Waldman SD (2015) Don’t Forget the Skin: 4 Common Dermatologic Manifestations of Internal Malignancy. J Oncol Med & Pract 1:102.doi:10.4172/jomp.1000102

Copyright: © 2015 Waldman RA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



The skin is a unique marker for malignancy as these cutaneous manifestation not only often precede the development of other symptoms, but also often cause patients to seek medical attention sooner than they would for other symptoms. Common cutaneous markers for malignancy include: acanthosis nigricans, carcinoid syndrome, Leser-Trelat sign, and necrolytic migratory erythema. Although these skin signs can also be associated with benign disease, the clinician should have a low threshold for carefully evaluating patients with a cutaneous complaint for underlying systemic disease, as these signs are often harbingers of underlying malignancy.


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